PAFAH1B3 and UNC119

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PAFAH1B3	UNC119
Description		platelet activating factor acetylhydrolase 1b catalytic subunit 3	unc-119 lipid binding chaperone
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane	Spindle Pole Centrosome Cytosol Intercellular Bridge Synapse Spindle Midzone
	Molecular Function	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Identical Protein Binding Protein-containing Complex Binding Platelet-activating Factor Acetyltransferase Activity	Protein Binding Lipid Binding
	Biological Process	Lipid Metabolic Process Spermatogenesis Nervous System Development Brain Development Lipid Catabolic Process	Mitotic Cytokinesis Endocytosis Chemical Synaptic Transmission Nervous System Development Visual Perception Phototransduction Lipoprotein Transport Positive Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis
Pathways		COPI-independent Golgi-to-ER retrograde traffic
Drugs		(1R)-1,2,2-trimethylpropyl (R)-methylphosphinate
Diseases
GWAS
Interacting Genes		33 interacting genes: BRD7 CCDC90B CHMP7 COPS6 CRMP1 DDX24 ECH1 EEF1A1 ERG28 GAPDH GBP2 GDF9 HSPH1 IGSF21 LNX1 LRIF1 MED31 PAFAH1B1 PAFAH1B2 PLEKHM1 RBM48 SDCBP2 SETDB1 SUMO4 TERF1 TERF2IP TLE1 TP53 TUBB2A UNC119 XRCC6 ZBTB16 ZHX1	93 interacting genes: AAGAB ALDH2 AMOT ANKRD24 ANXA1 ANXA3 ANXA7 ARL15 ARL2 ARL3 ARL4D ASH2L BCR BRIX1 BTBD2 C16orf74 CBX8 CCL18 CD247 CD3E CD4 CDC42 CDKN1A CDKN2C CETN3 CKMT2 CKS2 COX17 CYB561D2 EIF2S2 ERH FKBPL FXYD6 FYN GIPC2 GSTM4 HCK HLA-DQA1 HMGB1 HSPB3 HSPE1 ID2 IL5RA ITSN1 KDM1A LAMA4 LCK LIG4 LUC7L2 LYN MAP3K20 MAPK10 MAPK8IP2 MPHOSPH6 MRPS12 ORAI2 PAFAH1B3 PAPSS1 PCDHA4 PFN1 PHF10 PIN1 PLPP2 PPA1 PSMD11 PSMD2 PTPRS QTRT1 RAP1B RASSF6 RCC1 RFC5 RGL2 RPA2 RPS6KA5 RUFY3 S100A4 S100A8 SAT1 SEPHS1 SERPINB9 SMN1 SULT1E1 TK1 TP53BP2 TP53I3 TRDMT1 TSC22D1 UBE2B UBE2I UBQLN4 ZFP64 ZNF24
Entrez ID		5050	9094
HPRD ID		04354	04927
Ensembl ID		ENSG00000079462	ENSG00000109103
Uniprot IDs		A0A024R0L6 Q15102	K7EN86 Q13432
PDB IDs			3GQQ 3RBQ 4GOJ 4GOK 5L7K 6H6A
Enriched GO Terms of Interacting Partners?
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