OPRL1 and GPRASP1

Number of citations of the paper that reports this interaction (PubMedID 15086532)
34

Data Source:
BioGRID (pull down)

		OPRL1	GPRASP1
Description		opioid related nociceptin receptor 1	G protein-coupled receptor associated sorting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane Cytoplasmic Vesicle Neuron Projection	Cytosol
	Molecular Function	Nociceptin Receptor Activity G Protein-coupled Receptor Activity Protein Binding Protein C-terminus Binding Peptide Binding Neuropeptide Binding	Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Sensory Perception Sensory Perception Of Pain Response To Estradiol Positive Regulation Of Urine Volume Opioid Receptor Signaling Pathway Eating Behavior Estrous Cycle Negative Regulation Of Blood Pressure Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Positive Regulation Of Gastric Acid Secretion Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Sensory Perception Of Pain Regulation Of Locomotor Rhythm Conditioned Place Preference	Endosome To Lysosome Transport G Protein-coupled Receptor Catabolic Process
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events
Drugs		Buprenorphine Etorphine Epicept NP-1
Diseases
GWAS		Cerebrospinal AB1-42 levels in normal cognition ( 29274321) LDL peak particle diameter (total fat intake interaction) ( 26112879) Mean corpuscular volume ( 27863252) Medication use (HMG CoA reductase inhibitors) ( 31015401) Metabolic syndrome ( 31589552)
Interacting Genes		4 interacting genes: GNA14 GPRASP1 PNOC RGS19	47 interacting genes: ADRB1 ADRB2 AGTR1 ATXN7 C8orf33 CALCR CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 CRIP1 CXCR2 F2R F2RL1 GLP1R GLYAT GRM1 GRM5 GRM8 HGH1 HMOX2 HTR7 LAMTOR5 LRP2 MAP7D1 MLNR MTF2 OFD1 OPRD1 OPRK1 OPRL1 OPRM1 OXTR PBK PER1 PFDN1 SNAPIN STMN2 TAC3 TACR1 TACR2 TACR3 TBXA2R TFG TRAF4 VIPR1
Entrez ID		4987	9737
HPRD ID		03971	02333
Ensembl ID		ENSG00000125510	ENSG00000198932
Uniprot IDs		A0A5F9ZI64 P41146 Q8IXB0	Q5JY77
PDB IDs		4EA3 5DHG 5DHH
Enriched GO Terms of Interacting Partners?
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