TBC1D25 and MAP1LC3A

Number of citations of the paper that reports this interaction (PubMedID 22354992)
74

Data Source:
BioGRID (pull down)

		TBC1D25	MAP1LC3A
Description		TBC1 domain family member 25	microtubule associated protein 1 light chain 3 alpha
Image		No pdb structure
GO Annotations	Cellular Component	Autophagosome Cytoplasmic Vesicle	Autophagosome Membrane Late Endosome Autophagosome Cytosol Microtubule Organelle Membrane Intracellular Membrane-bounded Organelle Autolysosome Synapse
	Molecular Function	GTPase Activator Activity Protein Binding Rab GTPase Binding	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding
	Biological Process	Intracellular Protein Transport Autophagy Activation Of GTPase Activity Regulation Of Autophagosome Maturation	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Response To Iron(II) Ion Response To Lead Ion Macroautophagy Cellular Response To Amino Acid Starvation Response To Morphine Cellular Response To Hydrogen Peroxide Cellular Response To Copper Ion Autophagosome Maturation
Pathways		TBC/RABGAPs	Macroautophagy Pink/Parkin Mediated Mitophagy Receptor Mediated Mitophagy
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241)
Interacting Genes		8 interacting genes: FEZ1 FEZ2 GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B RAB2A	49 interacting genes: AKAP13 AMBRA1 ANK2 ANK3 APP ATG101 ATG13 ATG4B BNIP3L DVL2 EPHA7 FUNDC1 GPSM1 KIF15 KXD1 LMNB1 MAP1A MAP1S MDM2 MEFV NBR1 NEDD4 OPTN PIAS4 PRPF40A RABGAP1 RABGAP1L RB1CC1 RDH12 RETREG3 RTKN SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TP53INP1 TRIM21 TUBA4A ULK1
Entrez ID		4943	84557
HPRD ID		08948	03144
Ensembl ID		ENSG00000068354	ENSG00000101460
Uniprot IDs		B4DF03 Q3MII6	Q9H492
PDB IDs			3ECI 3WAL 3WAN 4ZDV 5CX3 5DPR
Enriched GO Terms of Interacting Partners?
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