NSF and FUNDC2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NSF	FUNDC2
Description		N-ethylmaleimide sensitive factor, vesicle fusing ATPase	FUN14 domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Golgi Stack Cytosol Plasma Membrane Postsynaptic Density Dendritic Shaft	Nucleus Mitochondrion Integral Component Of Mitochondrial Outer Membrane
	Molecular Function	SNARE Binding Protein Binding ATP Binding ATPase Activity Syntaxin-1 Binding Rab GTPase Binding Protein Kinase Binding PDZ Domain Binding Ionotropic Glutamate Receptor Binding ATPase Activity, Coupled Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Receptor Recycling Potassium Ion Transport Intracellular Protein Transport Exocytosis ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Regulation Of Exocytosis SNARE Complex Disassembly Golgi To Plasma Membrane Protein Transport Plasma Membrane Fusion Positive Regulation Of Protein Catabolic Process COPII Vesicle Coating Golgi Vesicle Docking	Autophagy Of Mitochondrion
Pathways		COPII-mediated vesicle transport Trafficking of GluR2-containing AMPA receptors COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs		1-Ethyl-Pyrrolidine-2,5-Dione
Diseases
GWAS		Alcohol use disorder (total score) ( 30336701) Body mass index ( 26426971) General factor of neuroticism ( 30867560) Handedness (Left-handed vs. non-left-handed) ( 30980028) Handedness (Right-handed vs. non-right-handed) ( 30980028) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 30054594) Macular thickness ( 30535121) Male-pattern baldness ( 28196072) Parkinson's disease ( 19915575 21812969) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Reaction time ( 29844566) Sense of smell ( 26632684) Thyroid stimulating hormone levels ( 30367059)
Interacting Genes		27 interacting genes: ARRB1 ASPSCR1 CD28 CEP126 DRD2 EIF3E ERG28 ESR1 FUNDC2 GABARAP GABARAPL2 GABBR1 GABBR2 GOSR1 GRIA2 GRIA3 LUC7L2 NAPA NAPG PTPN9 RAMP3 RPLP1 STX1A STX4 STX8 USO1 VAPA	11 interacting genes: ARL15 ASCC2 ATP13A2 EIF6 NACA NSF NUDT21 RGS1 SAT1 TP53I3 USP13
Entrez ID		4905	65991
HPRD ID		03380	06586
Ensembl ID		ENSG00000073969	ENSG00000165775
Uniprot IDs		A0A384MTI6 P46459	Q9BWH2
PDB IDs
Enriched GO Terms of Interacting Partners?
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