NSF and PTPN9

Number of citations of the paper that reports this interaction (PubMedID 15322554)
37

Data Source:
HPRD (in vitro)

		NSF	PTPN9
Description		N-ethylmaleimide sensitive factor, vesicle fusing ATPase	protein tyrosine phosphatase non-receptor type 9
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Golgi Stack Cytosol Plasma Membrane Postsynaptic Density Dendritic Shaft	Nucleoplasm Cytoplasm Neuron Projection Terminus
	Molecular Function	SNARE Binding Protein Binding ATP Binding ATPase Activity Syntaxin-1 Binding Rab GTPase Binding Protein Kinase Binding PDZ Domain Binding Ionotropic Glutamate Receptor Binding ATPase Activity, Coupled Protein-containing Complex Binding Metal Ion Binding	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Positive Regulation Of Receptor Recycling Potassium Ion Transport Intracellular Protein Transport Exocytosis ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Regulation Of Exocytosis SNARE Complex Disassembly Golgi To Plasma Membrane Protein Transport Plasma Membrane Fusion Positive Regulation Of Protein Catabolic Process COPII Vesicle Coating Golgi Vesicle Docking	Protein Dephosphorylation Negative Regulation Of Neuron Projection Development Peptidyl-tyrosine Dephosphorylation Cellular Response To Cytokine Stimulus Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		COPII-mediated vesicle transport Trafficking of GluR2-containing AMPA receptors COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	Interleukin-37 signaling
Drugs		1-Ethyl-Pyrrolidine-2,5-Dione
Diseases
GWAS		Alcohol use disorder (total score) ( 30336701) Body mass index ( 26426971) General factor of neuroticism ( 30867560) Handedness (Left-handed vs. non-left-handed) ( 30980028) Handedness (Right-handed vs. non-right-handed) ( 30980028) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 30054594) Macular thickness ( 30535121) Male-pattern baldness ( 28196072) Parkinson's disease ( 19915575 21812969) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Reaction time ( 29844566) Sense of smell ( 26632684) Thyroid stimulating hormone levels ( 30367059)	Estimated glomerular filtration rate ( 31015462) Height ( 25429064 31562340 20189936) Type 2 diabetes ( 30297969)
Interacting Genes		27 interacting genes: ARRB1 ASPSCR1 CD28 CEP126 DRD2 EIF3E ERG28 ESR1 FUNDC2 GABARAP GABARAPL2 GABBR1 GABBR2 GOSR1 GRIA2 GRIA3 LUC7L2 NAPA NAPG PTPN9 RAMP3 RPLP1 STX1A STX4 STX8 USO1 VAPA	10 interacting genes: AGTRAP CMTM5 CREB3 GHR LMNA MAL2 NSF REEP6 RTN3 STX6
Entrez ID		4905	5780
HPRD ID		03380	02864
Ensembl ID		ENSG00000073969	ENSG00000169410
Uniprot IDs		A0A384MTI6 P46459	P43378 Q6IQ43
PDB IDs			2PA5 4GE2 4GE5 4GE6 4ICZ
Enriched GO Terms of Interacting Partners?
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