ATP1B1 and SERPINC1

		ATP1B1	SERPINC1
Description		ATPase Na+/K+ transporting subunit beta 1	serpin family C member 1
Image		No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Sodium:potassium-exchanging ATPase Complex Caveola Intercalated Disc Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane T-tubule Organelle Membrane Sperm Flagellum Sarcolemma Extracellular Exosome Extracellular Vesicle	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	ATPase Activator Activity Sodium:potassium-exchanging ATPase Activity Protein Binding ATP Binding Protein C-terminus Binding Drug Binding ATPase Activity Cation-transporting ATPase Activity Protein Kinase Binding MHC Class II Protein Complex Binding Potassium Ion Binding Sodium Ion Binding Protein Heterodimerization Activity ATPase Binding	Protease Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding
	Biological Process	Response To Hypoxia Cellular Calcium Ion Homeostasis Cellular Sodium Ion Homeostasis Cell Adhesion Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Regulation Of Gene Expression Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Cellular Potassium Ion Homeostasis Positive Regulation Of ATPase Activity Ion Transmembrane Transport Sodium Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane Protein Transport Into Plasma Membrane Raft ATP Metabolic Process Protein Stabilization Leukocyte Migration Relaxation Of Cardiac Muscle Cardiac Muscle Contraction Potassium Ion Transmembrane Transport Protein Localization To Plasma Membrane Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cation Transmembrane Transport Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Export Across Plasma Membrane Positive Regulation Of Calcium:sodium Antiporter Activity Positive Regulation Of Potassium Ion Import Regulation Of Cardiac Conduction Potassium Ion Import Across Plasma Membrane	Acute Inflammatory Response To Antigenic Stimulus Response To Nutrient Lactation Blood Coagulation Negative Regulation Of Endopeptidase Activity Post-translational Protein Modification Cellular Protein Metabolic Process Regulation Of Blood Coagulation, Intrinsic Pathway
Pathways		Basigin interactions Ion homeostasis Ion transport by P-type ATPases	Intrinsic Pathway of Fibrin Clot Formation Common Pathway of Fibrin Clot Formation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs			Ardeparin Fondaparinux sodium Heparin Enoxaparin N-Formylmethionine SR-123781A Sulodexide Dalteparin Tinzaparin Nadroparin Copper Antithrombin III human
Diseases			Inherited thrombophilia
GWAS		Coronary artery disease ( 29212778) Electrocardiographic traits ( 25055868) Fuchs's corneal dystrophy ( 28358029) Mitochondrial DNA levels ( 25240745) QT interval ( 23166209 29213071 24952745 19305409) Rosacea symptom severity ( 29771307)	Experiencing mood swings ( 29500382) Heel bone mineral density ( 30598549)
Interacting Genes		26 interacting genes: BACE1 BARD1 BRCA1 CD84 CREG1 CRIP2 DDAH2 EGFR EZH2 FXYD1 FXYD7 GCH1 HCRTR1 KMT2B LRIF1 NDRG2 PAXIP1 PRRX1 PSME1 SERPINC1 THOC1 TM4SF1 TRIM14 TRMT2A TSC22D2 USP4	6 interacting genes: ATP1B1 F2 KLK2 KLK6 PLG SDC2
Entrez ID		481	462
HPRD ID		01663	00122
Ensembl ID		ENSG00000143153	ENSG00000117601
Uniprot IDs		A3KLL5 P05026	A0A024R944 P01008
PDB IDs			1ANT 1ATH 1AZX 1BR8 1DZG 1DZH 1E03 1E04 1E05 1JVQ 1LK6 1NQ9 1OYH 1R1L 1SR5 1T1F 1TB6 2ANT 2B4X 2B5T 2BEH 2GD4 2HIJ 2ZNH 3EVJ 3KCG 4EB1
Enriched GO Terms of Interacting Partners?
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