ATP12A and PPIB

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ATP12A	PPIB
Description		ATPase H+/K+ transporting non-gastric alpha2 subunit	peptidylprolyl isomerase B
Image		No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Potassium:proton Exchanging ATPase Complex Basolateral Plasma Membrane	Nucleus Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Smooth Endoplasmic Reticulum Focal Adhesion Membrane Protein-containing Complex Endoplasmic Reticulum Chaperone Complex Melanosome Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Sodium:potassium-exchanging ATPase Activity ATP Binding Potassium:proton Exchanging ATPase Activity Metal Ion Binding	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Collagen Binding Cyclosporin A Binding Unfolded Protein Binding RNA Polymerase Binding
	Biological Process	Cellular Sodium Ion Homeostasis Regulation Of PH Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Cellular Potassium Ion Homeostasis Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane Proton Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Protein Peptidyl-prolyl Isomerization Positive Regulation Of Multicellular Organism Growth Protein Refolding Positive Regulation By Host Of Viral Process Positive Regulation By Host Of Viral Genome Replication Protein Stabilization Bone Development Chaperone-mediated Protein Folding Regulation Of Post-translational Protein Modification
Pathways		Ion transport by P-type ATPases	Collagen biosynthesis and modifying enzymes
Drugs			L-Proline 1,4-Dithiothreitol
Diseases			Osteogenesis imperfecta
GWAS		Diastolic blood pressure ( 30224653) Meconium ileus in cystic fibrosis ( 30807572) Obesity-related traits ( 23251661)
Interacting Genes		3 interacting genes: GNAI3 NPY PPIB	19 interacting genes: APOB ATP12A BANP CAMLG DNM2 ESR1 GLP1R H3-4 IRF3 MDM2 PEX19 PRL SGTA SGTB STAT5A TP53 UBQLN1 UBQLN4 VKORC1
Entrez ID		479	5479
HPRD ID		01667	00458
Ensembl ID		ENSG00000075673	ENSG00000166794
Uniprot IDs		B4E0R9 P54707	P23284
PDB IDs			1CYN 3ICH 3ICI
Enriched GO Terms of Interacting Partners?
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