ATP12A and NPY

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ATP12A	NPY
Description		ATPase H+/K+ transporting non-gastric alpha2 subunit	neuropeptide Y
Image		No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Potassium:proton Exchanging ATPase Complex Basolateral Plasma Membrane	Extracellular Region Extracellular Space Cell Golgi Apparatus Synapse Neuronal Dense Core Vesicle
	Molecular Function	Sodium:potassium-exchanging ATPase Activity ATP Binding Potassium:proton Exchanging ATPase Activity Metal Ion Binding	G Protein-coupled Receptor Binding G Protein-coupled Receptor Activity Signaling Receptor Binding Hormone Activity Neuropeptide Hormone Activity Calcium Channel Regulator Activity
	Biological Process	Cellular Sodium Ion Homeostasis Regulation Of PH Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Cellular Potassium Ion Homeostasis Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane Proton Transmembrane Transport Potassium Ion Import Across Plasma Membrane	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Chemical Synaptic Transmission Feeding Behavior Regulation Of Blood Pressure Adult Feeding Behavior Central Nervous System Neuron Development Cerebral Cortex Development Neuron Projection Development Positive Regulation Of Appetite Intestinal Epithelial Cell Differentiation
Pathways		Ion transport by P-type ATPases	Peptide ligand-binding receptors G alpha (i) signalling events FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
Drugs			Alpha-Aminoisobutyric Acid L-Tyrosinamide
Diseases
GWAS		Diastolic blood pressure ( 30224653) Meconium ileus in cystic fibrosis ( 30807572) Obesity-related traits ( 23251661)	Aggressive periodontitis (sex interaction) ( 25256105) Chronotype ( 30696823) Morning person ( 30696823) Periodontitis ( 23459936) Vitamin D levels ( 25208829)
Interacting Genes		3 interacting genes: GNAI3 NPY PPIB	15 interacting genes: ATP12A BAG6 GHRL MC4R MEP1A MEP1B NPFF NPFFR2 NPY1R NPY2R NPY4R NPY5R NR1H2 PMCH UBQLN1
Entrez ID		479	4852
HPRD ID		01667	01214
Ensembl ID		ENSG00000075673	ENSG00000122585
Uniprot IDs		B4E0R9 P54707	A4D158 P01303
PDB IDs			1QFA 1RON
Enriched GO Terms of Interacting Partners?
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