ATP1A2 and TPT1

Number of citations of the paper that reports this interaction (PubMedID 15383549)
31

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		ATP1A2	TPT1
Description		ATPase Na+/K+ transporting subunit alpha 2	tumor protein, translationally-controlled 1
Image		No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Endosome Plasma Membrane Sodium:potassium-exchanging ATPase Complex Caveola Intercalated Disc Membrane T-tubule Organelle Membrane Cell Projection Neuronal Cell Body Dendritic Spine Extracellular Vesicle	Spindle Pole Extracellular Space Cell Nucleus Cytoplasm Multivesicular Body Cytosol Cytoplasmic Microtubule Extracellular Exosome
	Molecular Function	Sodium:potassium-exchanging ATPase Activity Protein Binding ATP Binding Drug Binding Phosphatase Activity ATPase Activity Cation-transporting ATPase Activity Potassium Ion Binding Sodium Ion Binding Protein Heterodimerization Activity Chaperone Binding Steroid Hormone Binding	RNA Binding Calcium Ion Binding Protein Binding
	Biological Process	Neurotransmitter Uptake Behavioral Fear Response Regulation Of The Force Of Heart Contraction Regulation Of Respiratory Gaseous Exchange By Neurological System Process Potassium Ion Transport Sodium Ion Transport Cellular Sodium Ion Homeostasis Regulation Of Muscle Contraction Regulation Of Smooth Muscle Contraction Regulation Of Striated Muscle Contraction Regulation Of Blood Pressure Adult Locomotory Behavior Visual Learning Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Response To Auditory Stimulus Dephosphorylation Regulation Of Vasoconstriction Amygdala Development Olfactory Cortex Development Cellular Potassium Ion Homeostasis Ion Transmembrane Transport Response To Nicotine Locomotory Exploration Behavior Sodium Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane Locomotion Negative Regulation Of Heart Contraction Positive Regulation Of Heart Contraction Negative Regulation Of Striated Muscle Contraction ATP Metabolic Process Negative Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Glutamate Uptake Involved In Transmission Of Nerve Impulse Regulation Of Synaptic Transmission, Glutamatergic Relaxation Of Cardiac Muscle Cardiac Muscle Contraction Cellular Response To Mechanical Stimulus Cellular Response To Steroid Hormone Stimulus Potassium Ion Transmembrane Transport Regulation Of Cardiac Muscle Cell Contraction Membrane Repolarization Membrane Depolarization During Cardiac Muscle Cell Action Potential Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cation Transmembrane Transport Proton Transmembrane Transport Negative Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Calcium:sodium Antiporter Activity Response To Glycoside Regulation Of Cardiac Conduction Potassium Ion Import Across Plasma Membrane	Calcium Ion Transport Cellular Calcium Ion Homeostasis Response To Virus Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways		Ion homeostasis Ion transport by P-type ATPases
Drugs		Ouabain	Calcium Citrate Calcium Phosphate
Diseases		Alternating hemiplegia of childhood Familial or sporadic hemiplegic migraine
GWAS		Response to antipsychotic treatment ( 23241943)	Type 2 diabetes ( 25760438)
Interacting Genes		1 interacting genes: TPT1	30 interacting genes: APP ATP1A1 ATP1A2 BCL2L1 CALM1 DBN1 EEF1A1 EEF1A2 EEF1B2 EEF1D FANCA HSPB1 IKBKG LIG4 MCL1 MCPH1 MDM2 MLC1 NKX3-1 NOTCH3 PER2 PLK1 RBBP6 RPLP1 SNX6 SPP1 STEAP3 TRIP13 TUBB2A VHL
Entrez ID		477	7178
HPRD ID		01665	15979
Ensembl ID		ENSG00000018625	ENSG00000133112
Uniprot IDs		A0A0S2Z3W6 P50993	A0A024RDY2 A0A0B4J2C3 A0A0P1J1R0 P13693
PDB IDs			1YZ1 2HR9 3EBM 4Z9V 5O9L 5O9M
Enriched GO Terms of Interacting Partners?
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