RERE and ZMYND8

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RERE	ZMYND8
Description		arginine-glutamic acid dipeptide repeats	zinc finger MYND-type containing 8
Image
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleus	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Dendritic Spine Dendritic Shaft
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding DNA Binding Chromatin Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding Methylated Histone Binding Protein N-terminus Binding Repressing Transcription Factor Binding Lysine-acetylated Histone Binding
	Biological Process	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Cerebellar Purkinje Cell Layer Maturation Cerebellar Granule Cell Precursor Proliferation Radial Glia Guided Migration Of Purkinje Cell Branching Morphogenesis Of A Nerve Dendrite Morphogenesis Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Nucleic Acid-templated Transcription	Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Migration Positive Regulation Of Filopodium Assembly Positive Regulation Of Dendritic Spine Development Modulation Of Excitatory Postsynaptic Potential Regulation Of Postsynaptic Density Protein 95 Clustering Positive Regulation Of Dendritic Spine Maintenance Negative Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Asthma ( 31361310 30929738 31619474) Asthma (adult onset) ( 30929738) Asthma (moderate or severe) ( 30552067) Asthma and major depressive disorder ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Autism spectrum disorder or schizophrenia ( 28540026) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Depression ( 29700475) Diastolic blood pressure ( 27841878) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Feeling miserable ( 29500382) Femoral neck bone mineral density ( 22504420) Heel bone mineral density ( 30598549 28869591) Hippocampal volume in normal cognition ( 29274321) Loneliness ( 31518406) Lymphocyte counts ( 27863252) Major depressive disorder ( 27479909) Medication use (adrenergics, inhalants) ( 31015401) Neutrophil percentage of granulocytes ( 27863252) Optic cup area ( 25631615 28073927) Schizophrenia ( 28991256 29483656 30285260) Smoking initiation ( 30617275) Smoking status (ever vs never smokers) ( 30643258) Sum eosinophil basophil counts ( 27863252) Systolic blood pressure ( 30578418) Tonsillectomy ( 27182965 28928442) Total body bone mineral density ( 29304378) Upper eyelid morphology ( 29921221) Vertical cup-disc ratio ( 20548946 25241763) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Vitiligo ( 20410501 27723757) White blood cell count ( 27863252)	Mean platelet volume ( 27863252) Metabolite levels ( 23823483) Migraine ( 27182965) Parahippocampal gyrus volume ( 31530798) Response to protease inhibitor treatment in hepatitis c (bilirubin toxicity) ( 24503447) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		20 interacting genes: ALG13 ATN1 CBFA2T2 ECM1 EFEMP1 EFEMP2 EHMT2 H3C14 KAT6A KRTAP4-12 LZTR1 NR2E1 PLSCR1 PRRC2A PRRC2B PSMA3 RBFOX2 TRIM22 TRIP6 ZMYND8	12 interacting genes: ATN1 CSNK1E FHOD1 H3C1 H4C1 PBXIP1 PRKCB RERE SPOP USP7 ZBTB7A ZFYVE9
Entrez ID		473	23613
HPRD ID		05566	10166
Ensembl ID		ENSG00000142599	ENSG00000101040
Uniprot IDs		Q9P2R6	A0A087WVZ6 A6H8Y8 Q2HXV5 Q569J9 Q9ULU4
PDB IDs		2YQK	4COS 5B73 5MQ4 5Y1Z
Enriched GO Terms of Interacting Partners?
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