MYOG and EIF4E2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MYOG	EIF4E2
Description		myogenin	eukaryotic translation initiation factor 4E family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Protein-DNA Complex	Cytosol MRNA Cap Binding Complex Eukaryotic Translation Initiation Factor 4F Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Chromatin DNA Binding Sequence-specific DNA Binding Protein Dimerization Activity E-box Binding	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ubiquitin Protein Ligase Binding
	Biological Process	Ossification Cell Cycle Skeletal Muscle Tissue Development Negative Regulation Of Cell Proliferation Response To Gravity Positive Regulation Of Myotube Differentiation Skeletal Muscle Atrophy Positive Regulation Of Muscle Atrophy Regulation Of Skeletal Muscle Satellite Cell Proliferation Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Striated Muscle Atrophy Response To Denervation Involved In Regulation Of Muscle Adaptation Skeletal Muscle Cell Differentiation Muscle Cell Fate Commitment MRNA Transcription By RNA Polymerase II Skeletal Muscle Tissue Regeneration Myoblast Differentiation Positive Regulation Of Myoblast Differentiation Negative Regulation Of Glycolytic Process Positive Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Muscle Cell Differentiation Positive Regulation Of Cell Cycle Arrest Cellular Response To Magnetism Cellular Response To Lithium Ion Cellular Response To Retinoic Acid Cellular Response To Tumor Necrosis Factor Cellular Response To Growth Factor Stimulus Cellular Response To Estradiol Stimulus Regulation Of Myoblast Fusion Positive Regulation Of Myoblast Fusion Positive Regulation Of Oxidative Phosphorylation	In Utero Embryonic Development Translational Initiation Negative Regulation Of Translation
Pathways		Myogenesis Myogenesis	ISG15 antiviral mechanism
Drugs
Diseases
GWAS		Asthma ( 30929738) Asthma (childhood onset) ( 30929738)	Height ( 25282103) Non-small cell lung cancer (survival) ( 21079520)
Interacting Genes		36 interacting genes: BBS4 CALM1 CALM2 CALM3 CARM1 CCDC28A CDH18 CLUAP1 CSRP3 EIF4E2 FBXO7 FTL H2AP HNF1A ID1 ID2 ID3 IKBIP MAPK3 MDFI MEF2A MEF2C MLH1 PACRGL POLR2C PRMT5 SEPTIN5 SP1 SRF TAF6L TCF3 TRIM43 TTC25 TTC32 TXNDC9 YME1L1	51 interacting genes: ADAMTSL4 AMOTL2 APP ARIH1 CAB39 CARD9 CBY2 CCL24 CDR2 EIF4EBP1 EIF4EBP3 EIF4ENIF1 FBXO25 GIGYF1 HOMEZ KRT13 KRT19 KRT20 KRT31 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 MAGED1 MAPRE3 MDFI MIPOL1 MVK MYOG NECAB2 NOTCH2NLA PDE4DIP PRDM14 REL SAG SP140 SPAG5 SPRY2 TADA2A TCF4 TGFBRAP1 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 USP54 ZBTB9
Entrez ID		4656	9470
HPRD ID		01167	05798
Ensembl ID		ENSG00000122180	ENSG00000135930
Uniprot IDs		P15173	B8ZZ50 B8ZZL3 B9A023 O60573 Q53RG0 Q59FE1
PDB IDs			2JGB 2JGC 5NVK 5NVL 5NVM 5NVN 5XLN
Enriched GO Terms of Interacting Partners?
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