MYO1C and RRN3

Number of citations of the paper that reports this interaction (PubMedID 15558034)
128

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vitro, in vivo)

		MYO1C	RRN3
Description		myosin IC	RRN3 homolog, RNA polymerase I transcription factor
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cell Nuclear Pore Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Microvillus Brush Border Basal Plasma Membrane Actin Cytoskeleton Membrane Lateral Plasma Membrane Unconventional Myosin Complex Nuclear Body Cytoplasmic Vesicle Membrane Filamentous Actin Vesicle Ruffle Membrane Membrane Raft Phagocytic Vesicle Stereocilium Membrane Extracellular Exosome	Nucleoplasm Nucleolus
	Molecular Function	Microfilament Motor Activity Signaling Receptor Binding Protein Binding Calmodulin Binding ATP Binding Protein C-terminus Binding Ral GTPase Binding Actin-dependent ATPase Activity Actin Filament Binding	RNA Polymerase I Core Binding RNA Polymerase I CORE Element Sequence-specific DNA Binding RNA Polymerase I General Transcription Initiation Factor Activity
	Biological Process	Protein Targeting Protein Targeting To Membrane Actin Filament Organization Vesicle Transport Along Actin Filament Positive Regulation Of Cell Migration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Gene Expression, Epigenetic MRNA Transport Cellular Response To Interferon-gamma Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Cellular Response To Insulin Stimulus Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Bicellular Tight Junction Assembly	RNA Polymerase I Preinitiation Complex Assembly In Utero Embryonic Development Transcription Initiation From RNA Polymerase I Promoter Nucleolus Organization Cytoplasm Organization Cell Proliferation Positive Regulation Of Neuron Projection Development Ribosome Biogenesis Positive Regulation Of Transcription, DNA-templated Homeostasis Of Number Of Cells Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of DNA-templated Transcription, Initiation
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Regulation of actin dynamics for phagocytic cup formation FCGR3A-mediated phagocytosis	RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737) Pulse pressure ( 30578418)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311)
Interacting Genes		5 interacting genes: BAZ1B CBL KHDRBS1 PTEN RRN3	10 interacting genes: CCNE1 CDK2 EIF3L MYO1C POLR1A POLR1B PPP2R2A TAF1A TAF1B TAF1C
Entrez ID		4641	54700
HPRD ID		09411	12004
Ensembl ID		ENSG00000197879	ENSG00000085721
Uniprot IDs		O00159	B7ZB55 F5H148 Q9NYV6
PDB IDs		4BYF
Enriched GO Terms of Interacting Partners?
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