RRN3 and POLR1B

Number of citations of the paper that reports this interaction (PubMedID 15004009)
156

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vitro, in vivo)

		RRN3	POLR1B
Description		RRN3 homolog, RNA polymerase I transcription factor	RNA polymerase I subunit B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus	Nucleoplasm Nucleolus RNA Polymerase I Complex Cytosol
	Molecular Function	RNA Polymerase I Core Binding RNA Polymerase I CORE Element Sequence-specific DNA Binding RNA Polymerase I General Transcription Initiation Factor Activity	DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Ribonucleoside Binding Metal Ion Binding
	Biological Process	RNA Polymerase I Preinitiation Complex Assembly In Utero Embryonic Development Transcription Initiation From RNA Polymerase I Promoter Nucleolus Organization Cytoplasm Organization Cell Proliferation Positive Regulation Of Neuron Projection Development Ribosome Biogenesis Positive Regulation Of Transcription, DNA-templated Homeostasis Of Number Of Cells Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of DNA-templated Transcription, Initiation	Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Embryo Implantation RRNA Transcription Nucleologenesis Positive Regulation Of Gene Expression, Epigenetic
Pathways		RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape	NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311)
Interacting Genes		10 interacting genes: CCNE1 CDK2 EIF3L MYO1C POLR1A POLR1B PPP2R2A TAF1A TAF1B TAF1C	14 interacting genes: AKT2 CCND1 EIF3L ESR1 GIT2 HDAC6 LDB1 LZTR1 MED20 NFKBIB POLR1E RPL37 RRN3 ZNF207
Entrez ID		54700	84172
HPRD ID		12004	06852
Ensembl ID		ENSG00000085721	ENSG00000125630
Uniprot IDs		B7ZB55 F5H148 Q9NYV6	B7Z1W6 Q9H9Y6
PDB IDs
Enriched GO Terms of Interacting Partners?
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