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MNAT1 and TRIM14
Number of citations of the paper that reports this interaction (PubMedID
29053956
)
17
Data Source:
BioGRID
(two hybrid)
MNAT1
TRIM14
Description
MNAT1 component of CDK activating kinase
tripartite motif containing 14
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Transcription Factor TFIIH Holo Complex
Cytosol
Cyclin-dependent Protein Kinase Activating Kinase Holoenzyme Complex
Mitochondrial Outer Membrane
Molecular Function
Protein Binding
DNA-dependent ATPase Activity
Zinc Ion Binding
RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity
Protein N-terminus Binding
Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
Molecular_function
Zinc Ion Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
G1/S Transition Of Mitotic Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair, Preincision Complex Assembly
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Protein Phosphorylation
Adult Heart Development
Ventricular System Development
Negative Regulation Of Apoptotic Process
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Smooth Muscle Cell Proliferation
Response To Calcium Ion
Protein-containing Complex Assembly
Negative Regulation Of DNA Helicase Activity
Negative Regulation Of Viral Transcription
Innate Immune Response
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Tat-mediated elongation of the HIV-1 transcript
NoRC negatively regulates rRNA expression
Formation of Incision Complex in GG-NER
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
Cyclin E associated events during G1/S transition
Cyclin D associated events in G1
Cyclin A/B1/B2 associated events during G2/M transition
Cyclin A:Cdk2-associated events at S phase entry
mRNA Capping
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Interferon gamma signaling
Drugs
Diseases
GWAS
Exhaled carbon monoxide levels in smokers with chronic obstructive pulmonary disease (
29631575
)
Immune reponse to smallpox (secreted IFN-alpha) (
22610502
)
Multiple sclerosis (
31604244
)
Interacting Genes
47 interacting genes:
BEX3
BRCA1
CDK7
COPS6
DMAP1
E2F1
EEF1A1
ERCC2
ERCC3
ESR1
FOXP1
GOLGA2
GTF2E2
GTF2H1
GTF2H2
HPS6
LRIF1
MAGEC2
MAGEE2
MCM7
MDM4
MKRN3
MTA1
NKX3-1
POLR2A
POU2F1
POU2F2
POU5F1
RB1
RBM48
RNF32
RNF41
RNF7
SUPT5H
TP53
TRIM14
TRIM17
TRIM2
TRIM21
TRIM26
TRIM31
TRIM34
TRIM39
TRIM5
TRIM9
TRIML1
USP2
52 interacting genes:
ABCF3
ALG13
AP3M1
ATP1B1
ATP1B3
ATP2A2
ATP5PB
ATP6V1H
CENPC
CSPP1
EIF3G
ETFBKMT
FAT1
HERC3
ITM2A
IVNS1ABP
KAT2B
KIF3A
LAMTOR1
MITD1
MNAT1
MRPL24
NCOR1
NDUFA9
NFAT5
NPC2
PCGF6
PDIA6
PHF11
PIM2
PLCG1
POLR2G
PPP2R3C
RAB5A
RAB9A
RBM33
RLF
RNF125
RNF20
SMARCB1
SMIM3
STK38
TAX1BP1
TMEM167A
UBE2B
UBE2N
UNK
WDR35
WRNIP1
ZC4H2
ZFP36L2
ZNF652
Entrez ID
4331
9830
HPRD ID
04042
05948
Ensembl ID
ENSG00000020426
ENSG00000106785
Uniprot IDs
A0A024R669
A0A024R688
P51948
A0A024R165
Q14142
PDB IDs
1G25
6NMI
6O9L
6O9M
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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