TRIM14 and WDR35

Number of citations of the paper that reports this interaction (PubMedID 29053956)
17

Data Source:
BioGRID (two hybrid)

		TRIM14	WDR35
Description		tripartite motif containing 14	WD repeat domain 35
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane	Cell Centrosome Cilium Axoneme Intraciliary Transport Particle A Ciliary Basal Body Ciliary Tip
	Molecular Function	Molecular_function Zinc Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Viral Transcription Innate Immune Response Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity	Response To Toxic Substance Negative Regulation Of Gene Expression Response To Lipopolysaccharide Intraciliary Retrograde Transport Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Nitric Oxide Biosynthetic Process Cilium Assembly Protein Localization To Cilium Cellular Response To Glucose Stimulus Cellular Response To Tumor Necrosis Factor Positive Regulation Of Release Of Cytochrome C From Mitochondria Liver Regeneration Negative Regulation Of Blood Vessel Diameter Cellular Response To Paclitaxel Cellular Response To Leukemia Inhibitory Factor
Pathways		Interferon gamma signaling	Hedgehog 'off' state Intraflagellar transport
Drugs
Diseases			Cranioectodermal dysplasia
GWAS		Multiple sclerosis ( 31604244)	Coronary heart disease ( 22751097) Facial morphology ( 29921221) Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		52 interacting genes: ABCF3 ALG13 AP3M1 ATP1B1 ATP1B3 ATP2A2 ATP5PB ATP6V1H CENPC CSPP1 EIF3G ETFBKMT FAT1 HERC3 ITM2A IVNS1ABP KAT2B KIF3A LAMTOR1 MITD1 MNAT1 MRPL24 NCOR1 NDUFA9 NFAT5 NPC2 PCGF6 PDIA6 PHF11 PIM2 PLCG1 POLR2G PPP2R3C RAB5A RAB9A RBM33 RLF RNF125 RNF20 SMARCB1 SMIM3 STK38 TAX1BP1 TMEM167A UBE2B UBE2N UNK WDR35 WRNIP1 ZC4H2 ZFP36L2 ZNF652	1 interacting genes: TRIM14
Entrez ID		9830	57539
HPRD ID		05948	15667
Ensembl ID		ENSG00000106785	ENSG00000118965
Uniprot IDs		A0A024R165 Q14142	Q9P2L0
PDB IDs
Enriched GO Terms of Interacting Partners?
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