ASGR1 and ASGR2

Number of citations of the paper that reports this interaction (PubMedID 2834401)
14

Data Source:
HPRD (in vivo)

		ASGR1	ASGR2
Description		asialoglycoprotein receptor 1	asialoglycoprotein receptor 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane	Plasma Membrane Integral Component Of Membrane Endoplasmic Reticulum Quality Control Compartment Perinuclear Region Of Cytoplasm
	Molecular Function	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding Metal Ion Binding	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding
	Biological Process	Receptor-mediated Endocytosis Viral Process Protein N-linked Glycosylation Via Asparagine Cellular Response To Extracellular Stimulus	Endocytosis Cell Surface Receptor Signaling Pathway Viral Process Protein N-linked Glycosylation Via Asparagine Bone Mineralization Regulation Of Protein Stability Lipid Homeostasis
Pathways		Asparagine N-linked glycosylation	Asparagine N-linked glycosylation
Drugs			Antihemophilic factor, human recombinant
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 22001757) Medication use (HMG CoA reductase inhibitors) ( 31015401) Serum alkaline phosphatase levels ( 31666285 29403010)	Blood protein levels ( 29875488) Congenital heart disease (maternal effect) ( 28468790) Total cholesterol levels ( 30275531)
Interacting Genes		14 interacting genes: APP ASGR2 CERS2 CLEC4G DHFR HIVEP1 HSP90AA1 HSP90B1 LAMTOR5 LMNA NLK RBBP6 TG VKORC1	8 interacting genes: ASGR1 CERS2 F8 GLP1R GLUD1 HES1 MROH5 VKORC1
Entrez ID		432	433
HPRD ID		00151	00152
Ensembl ID		ENSG00000141505	ENSG00000161944
Uniprot IDs		P07306 Q6FGQ5	P07307 Q7Z4G9
PDB IDs		1DV8 5JPV 5JQ1
Enriched GO Terms of Interacting Partners?
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