MIA2 and SEC24C

Number of citations of the paper that reports this interaction (PubMedID 21525241)
56

Data Source:
BioGRID (two hybrid)

		MIA2	SEC24C
Description		MIA SH3 domain ER export factor 2	SEC24 homolog C, COPII coat complex component
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Endoplasmic Reticulum Exit Site	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat
	Molecular Function	Protein Binding	SNARE Binding Protein Binding Zinc Ion Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Protein Secretion Cargo Loading Into Vesicle	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II COPII Vesicle Coating Cargo Loading Into COPII-coated Vesicle
Pathways		Cargo concentration in the ER	Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Crohn's disease ( 28067908) Self-rated health ( 27864402)
Interacting Genes		13 interacting genes: CCHCR1 CEP57 DGCR6 EMILIN1 GRB2 MAGEB18 PSMA3 RASAL2 SEC23A SEC24C SS18L1 TLE5 TTC23L	9 interacting genes: APP FBXO7 MIA2 MIA3 MOS SEC23A SEC23B SPP1 WIPF1
Entrez ID		4253	9632
HPRD ID		03680	06217
Ensembl ID		ENSG00000150527	ENSG00000176986
Uniprot IDs		Q4G155 Q59FD2 Q96PC5	A0A024QZM6 P53992
PDB IDs			3EH2
Enriched GO Terms of Interacting Partners?
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