SEC24C and MIA3

Number of citations of the paper that reports this interaction (PubMedID 19269366)
126

Data Source:
BioGRID (two hybrid)

		SEC24C	MIA3
Description		SEC24 homolog C, COPII coat complex component	MIA SH3 domain ER export factor 3
Image
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat	Golgi Membrane Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Endoplasmic Reticulum Exit Site
	Molecular Function	SNARE Binding Protein Binding Zinc Ion Binding	Protein Binding Cargo Receptor Activity
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II COPII Vesicle Coating Cargo Loading Into COPII-coated Vesicle	Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Leukocyte Migration Exocytosis ER To Golgi Vesicle-mediated Transport Endocytosis Endoplasmic Reticulum Organization Negative Regulation Of Cell Adhesion Protein Secretion Protein Transport Negative Regulation Of Cell Migration Cargo Loading Into Vesicle Wound Healing Lipoprotein Transport Post-translational Protein Modification Cellular Protein Metabolic Process Protein Localization To Endoplasmic Reticulum Exit Site Cargo Loading Into COPII-coated Vesicle Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus Negative Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Lymphocyte Migration
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Cargo concentration in the ER Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Crohn's disease ( 28067908) Self-rated health ( 27864402)	Coronary artery disease ( 29212778 30104761 26343387) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary heart disease ( 17634449 21378990) Myocardial infarction ( 26343387) Myocardial infarction (early onset) ( 19198609)
Interacting Genes		9 interacting genes: APP FBXO7 MIA2 MIA3 MOS SEC23A SEC23B SPP1 WIPF1	12 interacting genes: CACNA1A CEP55 COL7A1 FXR2 HSD17B14 ITGAX MTNR1B PRDM14 SEC16A SEC23A SEC24C TRIM27
Entrez ID		9632	375056
HPRD ID		06217	18918
Ensembl ID		ENSG00000176986	ENSG00000154305
Uniprot IDs		A0A024QZM6 P53992	Q5JRA6
PDB IDs		3EH2	5KYN 5KYU 5KYW
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?