MDH2 and WARS1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MDH2	WARS1
Description		malate dehydrogenase 2	tryptophanyl-tRNA synthetase 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Membrane Extracellular Exosome	Nucleus Cytoplasm Cytosol Protein-containing Complex Extracellular Exosome
	Molecular Function	RNA Binding L-malate Dehydrogenase Activity Protein Self-association Malate Dehydrogenase (NADP+) Activity	Tryptophan-tRNA Ligase Activity Protein Binding ATP Binding Kinase Inhibitor Activity Protein Kinase Binding Protein Domain Specific Binding Protein Homodimerization Activity
	Biological Process	Gluconeogenesis Tricarboxylic Acid Cycle Oxaloacetate Metabolic Process Malate Metabolic Process Internal Protein Amino Acid Acetylation NADH Metabolic Process Aerobic Respiration	Angiogenesis Negative Regulation Of Protein Phosphorylation Translation TRNA Aminoacylation For Protein Translation Tryptophanyl-tRNA Aminoacylation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Regulation Of Protein ADP-ribosylation Positive Regulation Of Protein Complex Assembly Regulation Of Angiogenesis
Pathways		Gluconeogenesis Citric acid cycle (TCA cycle)	Cytosolic tRNA aminoacylation
Drugs		NADH Citric Acid Xanthinol	L-Tryptophan Tryptophanyl-5'amp L-Tryptophanamide
Diseases
GWAS
Interacting Genes		8 interacting genes: CRYAB CS FH GOT2 HSPB1 NDUFS1 PC WARS1	9 interacting genes: APP CDK2AP2 DCAF13 DNMT3B EEF1A1 LIG4 MDH2 TERF1 UBC
Entrez ID		4191	7453
HPRD ID		01099	01845
Ensembl ID		ENSG00000146701	ENSG00000140105
Uniprot IDs		A0A024R4K3 B3KTM1 G3XAL0 P40926	A0A024R6K8 P23381
PDB IDs		2DFD 4WLE 4WLF 4WLN 4WLO 4WLU 4WLV	1O5T 1R6T 1R6U 1ULH 2AKE 2AZX 2DR2 2QUH 2QUI 2QUJ 2QUK 5UJI 5UJJ
Enriched GO Terms of Interacting Partners?
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