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WARS1

Description tryptophanyl-tRNA synthetase 1
Image
GO Annotations Cellular Component
  • Nucleus
  • Cytoplasm
  • Cytosol
  • Protein-containing Complex
  • Extracellular Exosome
Molecular Function
  • Tryptophan-tRNA Ligase Activity
  • Protein Binding
  • ATP Binding
  • Kinase Inhibitor Activity
  • Protein Kinase Binding
  • Protein Domain Specific Binding
  • Protein Homodimerization Activity
Biological Process
  • Angiogenesis
  • Negative Regulation Of Protein Phosphorylation
  • Translation
  • TRNA Aminoacylation For Protein Translation
  • Tryptophanyl-tRNA Aminoacylation
  • Negative Regulation Of Protein Kinase Activity
  • Negative Regulation Of Cell Proliferation
  • Positive Regulation Of Gene Expression
  • Regulation Of Protein ADP-ribosylation
  • Positive Regulation Of Protein Complex Assembly
  • Regulation Of Angiogenesis
Pathways
  • Cytosolic tRNA aminoacylation
Drugs
  • L-Tryptophan
  • Tryptophanyl-5'amp
  • L-Tryptophanamide
Diseases
GWAS
Interacting Genes 9 interacting genes: APP CDK2AP2 DCAF13 DNMT3B EEF1A1 LIG4 MDH2 TERF1 UBC
Entrez ID 7453
HPRD ID 01845
Ensembl ID ENSG00000140105
Uniprot IDs A0A024R6K8 P23381
PDB IDs 1O5T 1R6T 1R6U 1ULH 2AKE 2AZX 2DR2 2QUH 2QUI 2QUJ 2QUK 5UJI 5UJJ
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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