SMAD6 and SMAD7

  • Number of citations of the paper that reports this interaction (PubMedID 9256479)
  • 62
  • Data Source:
  • HPRD (in vitro, in vivo, two hybrid)

SMAD6

SMAD7

Description SMAD family member 6 SMAD family member 7
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma ( 29273806)
  • Asthma (adult onset) ( 31036433)
  • Asthma (childhood onset) ( 31036433)
  • Carpal tunnel syndrome ( 30833571)
  • Dental caries (decayed and filled deciduous teeth) ( 31533690)
  • Height ( 31562340)
  • Lung cancer (smoking interaction) ( 24658283)
  • Severe aortic features in Marfan syndrome ( 30087447)
  • Subcutaneous adipose tissue ( 22589738)
  • Waist-hip ratio ( 25673412)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes 16 interacting genes: BMPR1B HOXC8 MAP3K7 MAPK6 RNF111 RPS6KA5 RUNX2 SMAD1 SMAD7 SMURF1 SMURF2 STAMBP STRAP TAB1 TGFBR1 TOB1 59 interacting genes: ACVR1B AKT1 ASH1L AXIN1 AXIN2 BMPR1B CBL CTNNB1 CXXC5 DVL1 EP300 ERBIN HAT1 HEYL KDM2A MAP2K3 MAP2K6 MAP3K7 MAPK14 MBD1 MRTFB MYOD1 NEDD4L OTUD1 PARD3 PIAS1 PIAS4 RLIM RNF111 SASH3 SETD7 SIRT1 SMAD2 SMAD3 SMAD4 SMAD6 SMURF1 SMURF2 SOX13 SOX5 SOX7 STAMBP STAMBPL1 STRAP TAB1 TGFB1I1 TGFBR1 TGFBR2 TTF1 TTF2 UBE2L3 UCHL5 WWP2 XRCC6 YAP1 ZBTB11 ZBTB44 ZEB1 ZNF107
Entrez ID 4091 4092
HPRD ID 04240 04241
Ensembl ID ENSG00000137834 ENSG00000101665
Uniprot IDs O43541 B3KYA8 O15105
PDB IDs 2DJY 2KXQ 2LTV 2LTW 2LTX 2LTY 2LTZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?