ABLIM1 and KCNJ12

Number of citations of the paper that reports this interaction (PubMedID 15024025)
60

Data Source:
HPRD (in vitro)

		ABLIM1	KCNJ12
Description		actin binding LIM protein 1	potassium inwardly rectifying channel subfamily J member 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytoplasm Actin Cytoskeleton Lamellipodium	Plasma Membrane Integral Component Of Membrane Intrinsic Component Of Membrane
	Molecular Function	Actin Binding Protein Binding Metal Ion Binding Actin Filament Binding	Inward Rectifier Potassium Channel Activity Protein Binding
	Biological Process	Cytoskeleton Organization Visual Perception Animal Organ Morphogenesis Lamellipodium Assembly Cilium Assembly	Potassium Ion Transport Muscle Contraction Regulation Of Heart Contraction Regulation Of Ion Transmembrane Transport Protein Homotetramerization Cardiac Conduction Potassium Ion Import Across Plasma Membrane
Pathways		DCC mediated attractive signaling	Activation of G protein gated Potassium channels Classical Kir channels Phase 4 - resting membrane potential Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Dofetilide Yohimbine
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Taste perception (total score including 6-n-propylthiouracil) in obesity with metabolic syndrome ( 31005965)	Body mass index ( 28892062 25673413) Height ( 20881960 31562340) Waist-hip ratio ( 25673412)
Interacting Genes		21 interacting genes: ACTB ACTG1 APP BEGAIN CALCOCO2 CARD9 DAPK1 GOLGA2 HOOK2 KCNJ12 KRT15 LDOC1 LRRK2 MFHAS1 PTPRD SREBF2 TRAF2 TSC22D4 USHBP1 VIM YWHAG	16 interacting genes: ABLIM1 APBA1 CASK DLG1 DLG2 DLG3 DLG4 DMD DTNA LIN7A LIN7B LIN7C PRKACA SNTA1 SNTB1 SNTB2
Entrez ID		3983	3768
HPRD ID		03819	09083
Ensembl ID		ENSG00000099204	ENSG00000184185
Uniprot IDs		B3KSG3 B4DQA3 O14639	Q14500
PDB IDs
Enriched GO Terms of Interacting Partners?
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