KRTAP10-1 and ECE1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KRTAP10-1	ECE1
Description		keratin associated protein 10-1	endothelin converting enzyme 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Lysosomal Membrane Endosome Plasma Membrane External Side Of Plasma Membrane Membrane Integral Component Of Membrane Intrinsic Component Of Endosome Membrane Vesicle Weibel-Palade Body Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function		Endopeptidase Activity Metalloendopeptidase Activity Protein Binding Zinc Ion Binding Peptide Hormone Binding Protein Homodimerization Activity
	Biological Process	Keratinization	Positive Regulation Of Receptor Recycling Regulation Of Systemic Arterial Blood Pressure By Endothelin Heart Development Substance P Catabolic Process Bradykinin Catabolic Process Calcitonin Catabolic Process Protein Processing Peptide Hormone Processing Regulation Of Vasoconstriction Endothelin Maturation Hormone Catabolic Process Embryonic Digit Morphogenesis Ear Development Pharyngeal System Development
Pathways		Keratinization	Peptide ligand-binding receptors
Drugs			5-(2-hydroxyethyl)nonane-1,9-diol
Diseases
GWAS			Body mass index ( 28552196) Feeling worry ( 29500382) Height ( 25282103) Longevity (age >90th survival percentile) ( 31413261) Morning person ( 30696823) Obesity-related traits ( 23251661) Weight ( 28552196)
Interacting Genes		75 interacting genes: ADAMTSL4 AEN AMMECR1 AVPI1 BAHD1 BCL6B CARD9 CATSPER1 CBX2 CHIC2 CHRD CREB5 CXCL16 DAAM2 DHX57 DKK1 DOCK2 ECE1 FAM76B GLRX3 HOXA1 HPCAL1 HSD3B7 KRTAP10-3 KRTAP12-1 KRTAP2-4 KRTAP26-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE3E MAPKBP1 MEOX2 MOBP NECTIN2 NOTCH2NLA NPDC1 NR4A1 OTX1 PID1 PIN1 POM121L8P PRM2 PRPF31 RSPO2 SHFL SLC23A1 SLC6A20 SPATA8 SPRY1 SPRY2 TULP3 WT1 ZBTB24 ZNF101 ZNF124 ZNF264 ZNF286A ZNF329 ZNF417 ZNF433 ZNF439 ZNF440 ZNF559 ZNF572 ZNF581 ZNF587 ZNF785 ZSCAN12 ZSCAN26	11 interacting genes: AGT CALCA CLK1 CLK2 EDN1 KNG1 KRTAP10-1 KRTAP10-5 MTDH MTNR1A MYOC
Entrez ID		386677	1889
HPRD ID		11184	02690
Ensembl ID		ENSG00000215455	ENSG00000117298
Uniprot IDs		P60331	A0A024RAB0 A0A024RAB2 A1PUP8 P42892
PDB IDs			3DWB
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?