KRT1 and EVPL

Number of citations of the paper that reports this interaction (PubMedID 8999895)
28

Data Source:
HPRD (in vivo)

		KRT1	EVPL
Description		keratin 1	envoplakin
Image
GO Annotations	Cellular Component	Cornified Envelope Extracellular Region Extracellular Space Nucleus Cytosol Cytoskeleton Membrane Keratin Filament Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle Ficolin-1-rich Granule Lumen	Cornified Envelope Cytoplasm Cytosol Intermediate Filament Membrane Desmosome Intermediate Filament Cytoskeleton Extracellular Exosome
	Molecular Function	Protein Binding Carbohydrate Binding Structural Constituent Of Epidermis Signaling Receptor Activity Protein Heterodimerization Activity	Structural Molecule Activity Intermediate Filament Binding Cadherin Binding
	Biological Process	Complement Activation, Lectin Pathway Retina Homeostasis Response To Oxidative Stress Peptide Cross-linking Keratinization Fibrinolysis Neutrophil Degranulation Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Protein Heterotetramerization Establishment Of Skin Barrier Cornification	Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Wound Healing Intermediate Filament Cytoskeleton Organization Cornification
Pathways		Neutrophil degranulation Keratinization Formation of the cornified envelope	Formation of the cornified envelope
Drugs		Zinc Copper
Diseases		Epidermolytic palmoplantar keratoderma (EPPK) Ichthyosis hystrix, Curth-Macklin type Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE) Striate palmoplantar keratoderma
GWAS			Depressive symptom improvement ( 30468137) Metabolite levels ( 23823483)
Interacting Genes		21 interacting genes: CALB2 CSTA DSP EVPL F12 FANCA FANCC IVL KNG1 KRT15 KRT33B KRT5 LINC00839 LORICRIN MBL2 NINL PDE4DIP PI3 PRKCE UBE3A YWHAQ	14 interacting genes: CSTA DSP IVL KRT1 KRT10 KRT2 KRT5 LORICRIN PI3 PLEKHA5 PPL PSORS1C2 SPRR2A SPRR3
Entrez ID		3848	2125
HPRD ID		00763	03352
Ensembl ID		ENSG00000167768	ENSG00000167880
Uniprot IDs		P04264	B7ZLH8 K7EKI0 Q92817
PDB IDs		4ZRY 6E2J 6UUI	4QMD
Enriched GO Terms of Interacting Partners?
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