IRF2 and FKBP7

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		IRF2	FKBP7
Description		interferon regulatory factor 2	FKBP prolyl isomerase 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytosol Focal Adhesion	Endoplasmic Reticulum Lumen
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Calcium Ion Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Immune System Process Regulation Of Transcription, DNA-templated Blood Coagulation Cell Proliferation Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway	Protein Peptidyl-prolyl Isomerization
Pathways		Interferon gamma signaling Interferon alpha/beta signaling Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Acute kidney injury in critical illness ( 27576016) Adverse response to drug ( 30420678) Chronic lymphocytic leukemia ( 28165464) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Lewy body disease ( 25188341) Night sleep phenotypes ( 27126917) Nonsyndromic cleft lip ( 31609978)	Atrial fibrillation ( 30061737) Blood protein levels ( 30072576 29875488) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183)
Interacting Genes		22 interacting genes: APP ATG7 BRD7 CSNK2A1 EP300 FKBP7 FOXK1 HMGB1 HMGN1 IRF1 IRF2BP1 IRF2BP2 IRF8 KAT2A KAT2B MDM2 NFKB1 PPP3CB PRKACA RELA SPI1 STAT1	10 interacting genes: AGPS IRF2 PDE11A PEX19 PRMT6 RBM45 SGTA TTC30A TTC30B UBQLN4
Entrez ID		3660	51661
HPRD ID		00962	08451
Ensembl ID		ENSG00000168310	ENSG00000079150
Uniprot IDs		P14316	Q9Y680
PDB IDs
Enriched GO Terms of Interacting Partners?
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