IRF2 and FOXK1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		IRF2	FOXK1
Description		interferon regulatory factor 2	forkhead box K1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytosol Focal Adhesion	Nuclear Chromatin Cell Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding 14-3-3 Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Immune System Process Regulation Of Transcription, DNA-templated Blood Coagulation Cell Proliferation Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Cellular Glucose Homeostasis Muscle Organ Development Negative Regulation Of Autophagy Regulation Of Glucose Metabolic Process Viral Process Protein Deubiquitination Cell Differentiation Response To Starvation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Canonical Glycolysis
Pathways		Interferon gamma signaling Interferon alpha/beta signaling Factors involved in megakaryocyte development and platelet production	UCH proteinases
Drugs
Diseases
GWAS		Acute kidney injury in critical illness ( 27576016) Adverse response to drug ( 30420678) Chronic lymphocytic leukemia ( 28165464) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Lewy body disease ( 25188341) Night sleep phenotypes ( 27126917) Nonsyndromic cleft lip ( 31609978)	Cognitive decline rate in late mild cognitive impairment ( 26252872) Diastolic blood pressure ( 30224653) Disease progression in age-related macular degeneration ( 29346644) Emotional lability in attention deficit hyperactivity disorder ( 31085060) Heel bone mineral density ( 30598549) Itch intensity from mosquito bite ( 28199695) Mosquito bite size ( 28199695)
Interacting Genes		22 interacting genes: APP ATG7 BRD7 CSNK2A1 EP300 FKBP7 FOXK1 HMGB1 HMGN1 IRF1 IRF2BP1 IRF2BP2 IRF8 KAT2A KAT2B MDM2 NFKB1 PPP3CB PRKACA RELA SPI1 STAT1	2 interacting genes: IRF2 SRF
Entrez ID		3660	221937
HPRD ID		00962	18750
Ensembl ID		ENSG00000168310	ENSG00000164916
Uniprot IDs		P14316	P85037
PDB IDs
Enriched GO Terms of Interacting Partners?
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