IL3RA and SGK2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		IL3RA	SGK2
Description		interleukin 3 receptor subunit alpha	serum/glucocorticoid regulated kinase 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Receptor Complex	Nucleoplasm Cytosol
	Molecular Function	Cytokine Receptor Activity Interleukin-3 Receptor Activity Cytokine Binding	Protein Serine/threonine Kinase Activity ATP Binding Potassium Channel Regulator Activity Sodium Channel Regulator Activity
	Biological Process	MAPK Cascade Cytokine-mediated Signaling Pathway Cellular Response To Interleukin-3 Interleukin-3-mediated Signaling Pathway	Regulation Of Cell Growth Protein Phosphorylation Response To Oxidative Stress Peptidyl-serine Phosphorylation Positive Regulation Of Transporter Activity Ion Transmembrane Transport Intracellular Signal Transduction Regulation Of Cell Proliferation
Pathways		Interleukin-3, Interleukin-5 and GM-CSF signaling RAF/MAP kinase cascade Interleukin receptor SHC signaling	Stimuli-sensing channels
Drugs		Sargramostim
Diseases
GWAS		Schizophrenia ( 17522711)	Daytime sleep phenotypes ( 27126917)
Interacting Genes		15 interacting genes: CDC25A CDK1 CISH CSF2 CSF2RB FOXP1 GNA12 IL3 JAK1 JAK2 LNX1 NR0B2 PPP1CC SAE1 SGK2	6 interacting genes: APP DAPK1 IL3RA NEDD4 NEDD4L PDPK1
Entrez ID		3563	10110
HPRD ID		02392	06348
Ensembl ID		ENSG00000185291	ENSG00000101049
Uniprot IDs		P26951	Q9HBY8
PDB IDs		4JZJ 5UV8 5UWC
Enriched GO Terms of Interacting Partners?
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