IFIT1 and IFIT5

Number of citations of the paper that reports this interaction (PubMedID 21642987)
179

Data Source:
BioGRID (affinity chromatography technology, pull down)

		IFIT1	IFIT5
Description		interferon induced protein with tetratricopeptide repeats 1	interferon induced protein with tetratricopeptide repeats 5
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Host Cell	Cytosol Plasma Membrane IkappaB Kinase Complex Actin Cytoskeleton Ruffle Membrane Apical Part Of Cell
	Molecular Function	RNA Binding Protein Binding	TRNA Binding RNA Cap Binding Double-stranded DNA Binding RNA Binding Single-stranded RNA Binding Protein Binding Poly(U) RNA Binding
	Biological Process	Response To Virus Viral Process Intracellular Transport Of Viral Protein In Host Cell Negative Regulation Of Protein Binding Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication Regulation Of Defense Response To Virus Negative Regulation Of Helicase Activity Defense Response To Virus Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Cellular Response To Exogenous DsRNA	Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Interacting Genes		4 interacting genes: EIF3E IFIT2 IFIT3 IFIT5	17 interacting genes: A2M APOE CDC37 CHUK ECSIT IFIT1 IFIT3 IKBKG LONP1 MAST1 PRDX2 PSEN2 RAD23A RNF32 SARAF SRPK1 SRPK2
Entrez ID		3434	24138
HPRD ID		00983	17130
Ensembl ID		ENSG00000185745	ENSG00000152778
Uniprot IDs		P09914	Q13325
PDB IDs		4HOU 5UDI 5UDJ 5UDK 5UDL 5W5H 5W5I 6C6K	3ZGQ 4HOQ 4HOR 4HOS 4HOT 4J0U
Enriched GO Terms of Interacting Partners?
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