APOBEC1 and BAG4

Number of citations of the paper that reports this interaction (PubMedID 14559896)
9

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		APOBEC1	BAG4
Description		apolipoprotein B mRNA editing enzyme catalytic subunit 1	BAG cochaperone 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Cytosol Plasma Membrane
	Molecular Function	RNA Binding Cytidine Deaminase Activity Cytosine Deaminase Activity Protein Binding Enzyme Activator Activity Zinc Ion Binding Protein Domain Specific Binding MRNA 3'-UTR AU-rich Region Binding Ribonucleoprotein Complex Binding	RNA Binding Protein Binding Ubiquitin Protein Ligase Binding Chaperone Binding
	Biological Process	RNA Processing MRNA Processing Lipid Metabolic Process Triglyceride Metabolic Process Response To Osmotic Stress Cytidine Deamination Response To Zinc Ion Response To Gamma Radiation Cytidine To Uridine Editing MRNA Modification Cellular Response To Insulin Stimulus Regulation Of Cell Proliferation Lipoprotein Biosynthetic Process Lipoprotein Transport Positive Regulation Of Catalytic Activity Response To Ethanol MRNA Stabilization Response To Calcium Ion Defense Response To Virus DNA Cytosine Deamination DNA Demethylation Negative Regulation Of Triglyceride Metabolic Process Negative Regulation Of Methylation-dependent Chromatin Silencing Positive Regulation Of MRNA Modification	Protein Folding Positive Regulation Of Fibroblast Migration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of Cell Adhesion Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Protein Kinase B Signaling Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Protein Localization To Plasma Membrane Ruffle Assembly Regulation Of Cellular Response To Heat Negative Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
Pathways		mRNA Editing: C to U Conversion Formation of the Editosome	Regulation of HSF1-mediated heat shock response Signaling by FGFR1 in disease TNF signaling Signaling by plasma membrane FGFR1 fusions
Drugs
Diseases
GWAS		Body mass index ( 28552196) Creatine kinase levels ( 29403010) HDL cholesterol levels ( 28334899)	Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 29483656)
Interacting Genes		8 interacting genes: A1CF APOBEC2 BAG4 CELF2 DNAJB11 DND1 KPNA2 SYNCRIP	38 interacting genes: APOBEC1 ATAD2 BAP1 BCAS3 BCL2 BEX1 CASZ1 CCL5 DIRAS3 EPSTI1 ERRFI1 GLCE GRAP2 HSPA1A HSPA8 IL13RA2 IL24 ITIH5 KLK5 KLK7 KLK9 LRATD2 LYPD3 MRC2 MTA3 NAT2 PDLIM2 PLAT PRDM14 RASL10B RHOBTB2 RNF20 RPL22 SCGB3A1 TBC1D7 THRSP TNFRSF1A TNFRSF25
Entrez ID		339	9530
HPRD ID		02531	04861
Ensembl ID		ENSG00000111701	ENSG00000156735
Uniprot IDs		P41238	O95429
PDB IDs			1M62 1M7K
Enriched GO Terms of Interacting Partners?
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