HTR1A and HTR1D

Number of citations of the paper that reports this interaction (PubMedID 11854302)
15

Data Source:
HPRD (in vivo, in vitro)

		HTR1A	HTR1D
Description		5-hydroxytryptamine receptor 1A	5-hydroxytryptamine receptor 1D
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Dendrite Synapse	Plasma Membrane Integral Component Of Plasma Membrane Dendrite Synapse
	Molecular Function	G Protein-coupled Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity Serotonin Binding Receptor-receptor Interaction	G Protein-coupled Receptor Activity G Protein-coupled Serotonin Receptor Activity Neurotransmitter Receptor Activity
	Biological Process	Behavioral Fear Response G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting Serotonin Receptor Signaling Pathway Serotonin Receptor Signaling Pathway Chemical Synaptic Transmission Cell Proliferation Positive Regulation Of Cell Proliferation Regulation Of Serotonin Secretion Exploration Behavior Regulation Of Dopamine Metabolic Process Vasoconstriction Serotonin Metabolic Process Regulation Of Hormone Secretion Regulation Of Behavior	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Chemical Synaptic Transmission Intestine Smooth Muscle Contraction Regulation Of Locomotion Vasoconstriction Regulation Of Behavior G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways		Serotonin receptors G alpha (i) signalling events	Serotonin receptors G alpha (i) signalling events
Drugs		Eletriptan Ziprasidone Methysergide Cabergoline Ropinirole Zolmitriptan Amitriptyline Olanzapine Clozapine Loxapine Pramipexole Imipramine Chlorpromazine Buspirone Nortriptyline Amoxapine Propranolol Lisuride Trazodone Sumatriptan Ergotamine Apomorphine Trimipramine Risperidone Alprenolol Ondansetron Naratriptan Pindolol Dopamine Ergoloid mesylate Doxepin Nefazodone Desipramine Pergolide Bromocriptine Ketamine Quetiapine Aripiprazole Paliperidone Penbutolol Yohimbine Acepromazine Alverine Molindone Pipotiazine Thioproperazine Lysergic Acid Diethylamide Dapoxetine Bifeprunox Flibanserin Iloperidone Lesopitron Rotigotine MN-305 LI-301 Cariprazine Mianserin Asenapine Vilazodone Bopindolol Cinitapride Lurasidone Perospirone Vortioxetine Brexpiprazole Dosulepin Setiptiline Pardoprunox Tiapride	Eletriptan Ziprasidone Cabergoline Ropinirole Zolmitriptan Dihydroergotamine Amitriptyline Olanzapine Clozapine Loxapine Pramipexole Lisuride Sumatriptan Ergotamine Apomorphine Trimipramine Risperidone Almotriptan Naratriptan Rizatriptan Frovatriptan Ergoloid mesylate Pergolide Bromocriptine Ketamine Quetiapine Aripiprazole Paliperidone Yohimbine NXN-188 Setiptiline Tiapride
Diseases
GWAS		Alcohol and nicotine co-dependence ( 23216389) Body mass index ( 20935630) Bronchopulmonary dysplasia ( 23897914) Fasting insulin (dietary factor interaction) ( 24204828) Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828) White matter lesion progression ( 26451028) White matter lesion progression (adjusted for white matter lesion burden at baseline) ( 26451028)	Estimated glomerular filtration rate ( 31015462) Height ( 28552196 20881960)
Interacting Genes		8 interacting genes: FGFR1 GABBR2 GNAI3 GPR26 HTR1B HTR1D S1PR1 S1PR3	3 interacting genes: HTR1A HTR1B S1PR1
Entrez ID		3350	3352
HPRD ID		00190	01636
Ensembl ID		ENSG00000178394	ENSG00000179546
Uniprot IDs		A8K5W4 P08908 Q5ZGX3	P28221
PDB IDs
Enriched GO Terms of Interacting Partners?
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