HSPE1 and ZHX1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HSPE1	ZHX1
Description		heat shock protein family E (Hsp10) member 1	zinc fingers and homeoboxes 1
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Membrane Extracellular Exosome	Nuclear Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Binding Protein Binding ATP Binding Metal Ion Binding Unfolded Protein Binding Chaperone Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Osteoblast Differentiation Protein Folding Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Unfolded Protein Chaperone Cofactor-dependent Protein Refolding	Negative Regulation Of Transcription By RNA Polymerase II Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 25056061 29483656)
Interacting Genes		14 interacting genes: ALDH2 APLP1 CASP3 CRMP1 EEF1A1 ERG28 GBP2 HSPD1 LRIF1 SAT1 STK3 TLE1 UNC119 ZHX1	53 interacting genes: AKR1C3 AKT1 ATXN1 BARD1 BCL2L1 BHLHE40 BID CHD3 CREB1 CREBBP CSNK2A1 DDX39B DLST DYNLL1 EFNA2 ELL GADD45A GNG11 GSK3B HSPE1 IDH1 LAMA4 LYAR MPHOSPH6 NACA NFYA PAFAH1B3 PEX14 PIAS4 PIGC PNP PRPF40A PSMD11 SAT1 SERPINB9 SUMO1 SUMO2 TAL1 TALDO1 TARDBP TERF1 TNFRSF10C TOLLIP TP53 UBC UTP3 VIM WDR33 ZHX2 ZHX3 ZMYND11 ZNF33B ZYX
Entrez ID		3336	11244
HPRD ID		02535	10379
Ensembl ID		ENSG00000115541	ENSG00000165156
Uniprot IDs		A0A384N6A4 P61604	A0A024R9F1 Q9UKY1
PDB IDs		4PJ1	2ECB 2GHF 2LY9 3NAR
Enriched GO Terms of Interacting Partners?
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