HSPE1 and ERG28

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HSPE1	ERG28
Description		heat shock protein family E (Hsp10) member 1	ergosterol biosynthesis 28 homolog
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Membrane Extracellular Exosome	Integral Component Of Membrane Transport Vesicle
	Molecular Function	RNA Binding Protein Binding ATP Binding Metal Ion Binding Unfolded Protein Binding Chaperone Binding	Molecular_function Protein Binding, Bridging
	Biological Process	Osteoblast Differentiation Protein Folding Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Unfolded Protein Chaperone Cofactor-dependent Protein Refolding	Biological_process
Pathways
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 25056061 29483656)
Interacting Genes		14 interacting genes: ALDH2 APLP1 CASP3 CRMP1 EEF1A1 ERG28 GBP2 HSPD1 LRIF1 SAT1 STK3 TLE1 UNC119 ZHX1	66 interacting genes: ALDH2 ANXA1 ANXA7 AQP2 BAIAP2 BID BTBD2 CCDC106 CCL18 CDC42 CDK5RAP2 CELF3 CLN8 COX17 CRADD CREB1 CREB3 CSTF2 DYNLL1 FAS FCGR2B FXR1 GADD45A GSK3B HMGB1 HNRNPH3 HNRNPUL1 HSPE1 HYLS1 KLHL20 LMNA LSM2 MAPK8IP2 MPHOSPH6 MRPL38 MRPS12 MTNR1B NAT9 NDUFA4L2 NR1H2 NSF PAFAH1B3 PCDHA4 PEX2 PFN1 PHYHIP POLE2 POLR2C POLR3F PPP1R8 PQBP1 RAB27A RPS6KA6 S100A8 SAT1 SEPHS1 SERPINB9 SNRPB SNRPG SULT1E1 TFG TK1 TSC22D1 TTR ZFP64 ZNF24
Entrez ID		3336	11161
HPRD ID		02535	05201
Ensembl ID		ENSG00000115541	ENSG00000133935
Uniprot IDs		A0A384N6A4 P61604	Q6FII3 Q86TW5 Q9UKR5
PDB IDs		4PJ1
Enriched GO Terms of Interacting Partners?
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