HOXC8 and DLX2

Number of citations of the paper that reports this interaction (PubMedID 9111364)
76

Data Source:
BioGRID (pull down)

		HOXC8	DLX2
Description		homeobox C8	distal-less homeobox 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm Microtubule Cytoskeleton	Nuclear Chromatin Nucleus
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific DNA Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Single-stranded RNA Binding Protein Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Neuron Differentiation Skeletal System Morphogenesis	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Brain Development Embryo Development Proximal/distal Pattern Formation Subpallium Development Hippocampus Development Olfactory Bulb Development Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment Cerebral Cortex GABAergic Interneuron Fate Commitment Cell Differentiation Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Cell Differentiation Negative Regulation Of Notch Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Photoreceptor Cell Differentiation Embryonic Cranial Skeleton Morphogenesis Negative Regulation Of Oligodendrocyte Differentiation Branching Morphogenesis Of A Nerve Cartilage Development Positive Regulation Of Amacrine Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Breast cancer ( 23535729) Food allergy ( 29030101) Peanut allergy ( 29030101)
Interacting Genes		12 interacting genes: BMPR1A BTG2 DLX2 DLX5 GMNN HOMEZ JUN MSX1 RBPMS SMAD1 SMAD4 SMAD6	14 interacting genes: AVP DGCR6 DIP2A DLX5 GRN HOXC8 MSX1 MSX2 MVP NCOA2 PIK3R1 PRKN TSPOAP1 XRCC6
Entrez ID		3224	1746
HPRD ID		00856	00527
Ensembl ID		ENSG00000037965	ENSG00000115844
Uniprot IDs		P31273	Q07687 Q53QU7 X5D7D8
PDB IDs
Enriched GO Terms of Interacting Partners?
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