DLX2 and DGCR6

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		DLX2	DGCR6
Description		distal-less homeobox 2	DiGeorge syndrome critical region gene 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nucleus Extracellular Matrix
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Single-stranded RNA Binding Protein Binding Sequence-specific DNA Binding	Molecular_function
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Brain Development Embryo Development Proximal/distal Pattern Formation Subpallium Development Hippocampus Development Olfactory Bulb Development Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment Cerebral Cortex GABAergic Interneuron Fate Commitment Cell Differentiation Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Cell Differentiation Negative Regulation Of Notch Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Photoreceptor Cell Differentiation Embryonic Cranial Skeleton Morphogenesis Negative Regulation Of Oligodendrocyte Differentiation Branching Morphogenesis Of A Nerve Cartilage Development Positive Regulation Of Amacrine Cell Differentiation	Cell Adhesion Animal Organ Morphogenesis
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 23535729) Food allergy ( 29030101) Peanut allergy ( 29030101)	Metabolite levels ( 23823483) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259)
Interacting Genes		14 interacting genes: AVP DGCR6 DIP2A DLX5 GRN HOXC8 MSX1 MSX2 MVP NCOA2 PIK3R1 PRKN TSPOAP1 XRCC6	61 interacting genes: ADAMTSL4 AGTRAP APP ARNT2 C1orf94 C3orf62 CBLL1 CBY2 CCDC33 CEP126 CTBP1 DEUP1 DLGAP2 DLX2 DNPEP DOCK8 EFEMP2 EFHC2 ENKD1 FBF1 GOLGA2 GSE1 HGS HOMEZ IHO1 IKZF3 KLHL12 LZTS2 MBIP MEIS2 MEOX2 MIA2 MID2 MIPOL1 NAB2 NECAB2 NOTCH2NLA NQO2 NUP54 NUP62 PDLIM7 PRDM14 RABGEF1 REL RFX6 RIMBP3 SPRY2 SS18L1 TCF12 TCF4 TFIP11 TLE5 TRAF1 TRAF2 TRIM27 TUBGCP4 VCP ZBED1 ZC4H2 ZNF398 ZNF446
Entrez ID		1746	8214
HPRD ID		00527	03177
Ensembl ID		ENSG00000115844	ENSG00000183628
Uniprot IDs		Q07687 Q53QU7 X5D7D8	Q14129 X5D7D2
PDB IDs
Enriched GO Terms of Interacting Partners?
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