HNRNPH1 and KHSRP

Number of citations of the paper that reports this interaction (PubMedID 17643375)
195

Data Source:
BioGRID (pull down, affinity chromatography technology)

		HNRNPH1	KHSRP
Description		heterogeneous nuclear ribonucleoprotein H1	KH-type splicing regulatory protein
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Membrane Catalytic Step 2 Spliceosome	Exosome (RNase Complex) Nucleoplasm Cytosol Cytoplasmic Stress Granule Membrane
	Molecular Function	RNA Binding Protein Binding Poly(U) RNA Binding	DNA Binding RNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Processing Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Regulation Of RNA Splicing	RNA Splicing, Via Transesterification Reactions Regulation Of Transcription, DNA-templated MRNA Processing MRNA Catabolic Process RNA Splicing MiRNA Metabolic Process Negative Regulation Of Low-density Lipoprotein Particle Clearance Regulation Of MRNA Stability Negative Regulation Of Nitric Oxide Biosynthetic Process MRNA Transport Positive Regulation Of MRNA Catabolic Process 3'-UTR-mediated MRNA Destabilization Cellular Response To Cytokine Stimulus Regulation Of MiRNA Metabolic Process
Pathways		FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	ATF4 activates genes in response to endoplasmic reticulum stress KSRP (KHSRP) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA
Drugs		Copper	Resveratrol Artenimol
Diseases
GWAS		Daytime sleep phenotypes ( 27126917)
Interacting Genes		23 interacting genes: APBB1 CRMP1 DDX5 ERG HIPK3 HNRNPF HNRNPH3 KHSRP MTNR1A NCBP1 NCBP2 NDRG1 PIN1 RALY SF1 SF3B4 SREK1 SUMO2 SUMO4 TCERG1 TOM1L1 YWHAG YWHAQ	15 interacting genes: A1CF APBB1 BACE1 EXOSC2 EXOSC3 GADD45A GCC1 GSK3B HNRNPA1 HNRNPH1 KLHL12 PARN PTBP2 STK3 UBE2I
Entrez ID		3187	8570
HPRD ID		03021	10350
Ensembl ID		ENSG00000169045	ENSG00000088247
Uniprot IDs		A0A384MEJ3 P31943	Q92945
PDB IDs		2LXU 6DHS	2HH2 2HH3 2JVZ 2OPU 2OPV 4B8T
Enriched GO Terms of Interacting Partners?
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