HNRNPC and ZFYVE26

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HNRNPC	ZFYVE26
Description		heterogeneous nuclear ribonucleoprotein C	zinc finger FYVE-type containing 26
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Extracellular Region Nucleus Nucleoplasm Spliceosomal Complex Telomerase Holoenzyme Complex Cytosol Actin Cytoskeleton Membrane Protein-containing Complex Extracellular Exosome Catalytic Step 2 Spliceosome	Lysosomal Membrane Centrosome Midbody
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(U) RNA Binding Nucleosomal DNA Binding Identical Protein Binding Telomerase RNA Binding N6-methyladenosine-containing RNA Binding	Protein Binding Phosphatidylinositol-3-phosphate Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Splicing RNA Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase ATP-dependent Chromatin Remodeling 3'-UTR-mediated MRNA Stabilization	Mitotic Cytokinesis Double-strand Break Repair Via Homologous Recombination Regulation Of Cytokinesis
Pathways		SUMOylation of RNA binding proteins mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS		Bipolar disorder ( 31043756 21738484) Height ( 31562340)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Asthma (childhood onset) ( 31036433)
Interacting Genes		51 interacting genes: AP1M1 BARD1 BRCA1 BRCA2 BRIP1 BTRC CCDC85B CDKN2A CELF1 CSNK1A1 CSNK2A1 CSNK2A2 DHX9 EPS8 ERG ESR1 FAS FXR2 GRB2 IL7R KHDRBS3 KPNA2 KPNA3 KPNA4 KRAS LMO2 LMO3 PALB2 PDGFB PHKB PIN1 PJA1 PRKDC PTBP2 RAD51 RALY RALYL RBM41 SDCBP SF3B2 SMARCD1 SREK1 SRPK2 SUMO1 SUMO1P1 TRAF3 UBE2I YWHAE YWHAQ ZFYVE26 ZNF581	19 interacting genes: ALAS1 CEP44 GOLGA2 HNRNPC KRT15 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 MDFI PNMA1 PNMA5 SPAG5 SSX2IP TADA2A TDO2 TFIP11 TRAF1 USHBP1
Entrez ID		3183	23503
HPRD ID		01243	15734
Ensembl ID		ENSG00000092199	ENSG00000072121
Uniprot IDs		P07910	Q68DK2
PDB IDs		1TXP 1WF2 2MXY 2MZ1 3LN4
Enriched GO Terms of Interacting Partners?
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