HMGCL and MS4A7

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

		HMGCL	MS4A7
Description		3-hydroxy-3-methylglutaryl-CoA lyase	membrane spanning 4-domains A7
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Peroxisome Peroxisomal Matrix Cytosol Protein-containing Complex	Integral Component Of Membrane
	Molecular Function	Fatty-acyl-CoA Binding Magnesium Ion Binding Hydroxymethylglutaryl-CoA Lyase Activity Structural Molecule Activity Manganese Ion Binding Carboxylic Acid Binding Metal Ion Binding
	Biological Process	Liver Development Leucine Catabolic Process Protein Targeting To Peroxisome Lipid Metabolic Process Acyl-CoA Metabolic Process Mitochondrion Organization Response To Nutrient Response To Starvation Ketone Body Biosynthetic Process Response To Fatty Acid
Pathways		Synthesis of Ketone Bodies Peroxisomal protein import Peroxisomal protein import
Drugs		3-hydroxyglutaric acid
Diseases		3-Hydroxy-3-methylglutaryl-CoA lyase deficiency
GWAS		High light scatter reticulocyte count ( 27863252) Immature fraction of reticulocytes ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		9 interacting genes: ADAMTS10 ARL6IP1 DNAJA1 GTF2B HES1 HSD17B10 MS4A7 PEX5 RNF126	2 interacting genes: HMGCL SLC35F6
Entrez ID		3155	58475
HPRD ID		02003	07579
Ensembl ID		ENSG00000117305	ENSG00000166927
Uniprot IDs		P35914	A0A024R505 A0A024R556 Q9GZW8
PDB IDs		2CW6 3MP3 3MP4 3MP5
Enriched GO Terms of Interacting Partners?
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