KCNIP2 and KCND3

Number of citations of the paper that reports this interaction (PubMedID 12928444)
12

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		KCNIP2	KCND3
Description		potassium voltage-gated channel interacting protein 2	potassium voltage-gated channel subfamily D member 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Potassium Channel Complex Synapse	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Dendrite Sarcolemma Neuronal Cell Body GABA-ergic Synapse Integral Component Of Postsynaptic Specialization Membrane
	Molecular Function	A-type (transient Outward) Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity Ion Channel Binding ER Retention Sequence Binding Protein N-terminus Binding Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization	Voltage-gated Potassium Channel Activity A-type (transient Outward) Potassium Channel Activity Protein Binding Ion Channel Binding Metal Ion Binding Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization
	Biological Process	Detection Of Calcium Ion Potassium Ion Transport Muscle Contraction Signal Transduction Chemical Synaptic Transmission Regulation Of Heart Contraction Clustering Of Voltage-gated Potassium Channels Cardiac Conduction Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Potassium Ion Export Across Plasma Membrane Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Voltage-gated Potassium Channel Activity	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Protein Homooligomerization Cardiac Conduction Potassium Ion Transmembrane Transport Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Potassium Ion Export Across Plasma Membrane Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Ventricular Cardiac Muscle Cell Membrane Repolarization
Pathways		Phase 1 - inactivation of fast Na+ channels	Voltage gated Potassium channels Phase 1 - inactivation of fast Na+ channels
Drugs			Disopyramide Amitriptyline Imipramine Vernakalant Dalfampridine
Diseases
GWAS			Atrial fibrillation ( 28416822 30061737 29892015) Early cardiac repolarization ( 31600170 22683750) Immune reponse to smallpox (secreted IFN-alpha) ( 22610502) Medication use (opioids) ( 31015401) Multisite chronic pain ( 31194737) P wave duration ( 24850809) P wave terminal force ( 28794112) PR interval ( 30679814) Response to radiotherapy in cancer (late toxicity) ( 24785509) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		3 interacting genes: KCND2 KCND3 KCNIP1	2 interacting genes: KCNIP1 KCNIP2
Entrez ID		30819	3752
HPRD ID		06880	16104
Ensembl ID		ENSG00000120049	ENSG00000171385
Uniprot IDs		A0A2R8Y6D7 B3KSZ5 Q9NS61	A0A024R0C6 Q9UK17
PDB IDs			1S1G 2NZ0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?