HBZ and KHDRBS2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HBZ	KHDRBS2
Description		hemoglobin subunit zeta	KH RNA binding domain containing, signal transduction associated 2
Image			No pdb structure
GO Annotations	Cellular Component	Hemoglobin Complex Haptoglobin-hemoglobin Complex Extracellular Exosome	Nucleus Nucleoplasm
	Molecular Function	Peroxidase Activity Oxygen Carrier Activity Iron Ion Binding Protein Binding Oxygen Binding Heme Binding Haptoglobin Binding Organic Acid Binding	RNA Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding SH2 Domain Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Oxygen Transport Hydrogen Peroxide Catabolic Process Erythrocyte Maturation Cellular Oxidant Detoxification	MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome
Pathways			PTK6 Regulates Proteins Involved in RNA Processing
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Body mass index ( 26426971) Early cardiac repolarization ( 31600170) Hemoglobin levels ( 26366553) Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 29403010 27863252) Red blood cell count ( 29403010)	Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Chronotype ( 30696823) Corneal astigmatism ( 30306274) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Esophageal adenocarcinoma ( 27527254) Presence of antiphospholipid antibodies ( 27098658) Protein quantitative trait loci ( 18464913)
Interacting Genes		15 interacting genes: APP DOCK8 FGFR3 HBB HBD HNRNPD IKBKG KHDRBS2 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 NOTCH2NLA SP1 UPF2	34 interacting genes: AEN CATSPER1 CHTOP CIRBP DOCK2 EWSR1 GRAP2 GRB2 HBZ HNRNPK HNRNPLL KHDRBS3 LINC01018 MTA1 NABP1 NCOA5 NPDC1 PRMT1 PRPF31 PRR3 PSMF1 PTK6 RBM10 RBM3 RBMX SDCBP SPG7 SULT1A3 TMEM14B TYK2 TYMSOS YTHDC1 ZFC3H1 ZNF688
Entrez ID		3050	202559
HPRD ID		00794	13775
Ensembl ID		ENSG00000130656	ENSG00000112232
Uniprot IDs		P02008	Q5VWX1
PDB IDs		1JEB 3W4U
Enriched GO Terms of Interacting Partners?
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