SH3KBP1 and MVB12A

Number of citations of the paper that reports this interaction (PubMedID 16895919)
8

Data Source:
HPRD (in vivo)

		SH3KBP1	MVB12A
Description		SH3 domain containing kinase binding protein 1	multivesicular body subunit 12A
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Focal Adhesion Endocytic Vesicle Cytoplasmic Vesicle Membrane Neuron Projection Synapse	ESCRT I Complex Nucleoplasm Golgi Apparatus Centrosome Cytosol Endosome Membrane Late Endosome Membrane Vesicle Host Cell Extracellular Exosome
	Molecular Function	Protein Binding SH3 Domain Binding	Protein Binding Lipid Binding SH3 Domain Binding Ubiquitin Binding
	Biological Process	Endocytosis Apoptotic Process Cytoskeleton Organization Actin Filament Organization Cell-cell Signaling Axon Guidance Regulation Of Cell Shape Cell Migration Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of B Cell Activation Membrane Organization	Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Virus Maturation Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Receptor Catabolic Process Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding Intracellular Transport Of Virus
Pathways		EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Reelin signalling pathway InlB-mediated entry of Listeria monocytogenes into host cell Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS
Interacting Genes		44 interacting genes: ABI2 ARAP3 ARHGAP27 ASAP1 ASAP2 BCAR1 BLNK BMPR1B CAPZA1 CBL CBLB CD2 GRB2 HCK INPP5D ITSN2 MVB12A NEDD4 PAK2 PDCD6 PDCD6IP PIK3CA PIK3R1 PNMA5 PSMA3 SEPTIN2 SEPTIN6 SH3BP2 SH3GL2 SH3GL3 SH3GLB1 SH3GLB2 SHKBP1 SOS1 SPRY2 STAP1 SYNJ1 TAF6 TJP2 UBB UBC UBE2I ZBTB7B ZNF219	3 interacting genes: APP CD2AP SH3KBP1
Entrez ID		30011	93343
HPRD ID		02301	14298
Ensembl ID		ENSG00000147010	ENSG00000141971
Uniprot IDs		B7Z6E8 Q5JPT6 Q96B97	A0A024R7L6 Q96EY5
PDB IDs		2BZ8 2K6D 2K9G 2N64 2O2O 2YDL 5ABS
Enriched GO Terms of Interacting Partners?
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