A1CF and SYNCRIP

Number of citations of the paper that reports this interaction (PubMedID 11134005)
35

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		A1CF	SYNCRIP
Description		APOBEC1 complementation factor	synaptotagmin binding cytoplasmic RNA interacting protein
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Apolipoprotein B MRNA Editing Enzyme Complex	Nucleus Nucleoplasm Endoplasmic Reticulum Membrane CRD-mediated MRNA Stability Complex Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex GAIT Complex Ribonucleoprotein Complex
	Molecular Function	RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding	RNA Binding MRNA Binding Protein Binding Poly(A) Binding MRNA 5'-UTR Binding
	Biological Process	MRNA Processing Cytidine To Uridine Editing MRNA Modification Protein Stabilization	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Processing RNA Splicing Viral Process Negative Regulation Of Translation CRD-mediated MRNA Stabilization Cellular Response To Interferon-gamma
Pathways		mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Colorectal cancer or advanced adenoma ( 30510241) Estimated glomerular filtration rate ( 31152163 31015462 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate (creatinine) ( 28452372) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Interferon alpha levels in systemic lupus erythematosus ( 25338677) LDL cholesterol ( 30275531) Narcolepsy with cataplexy ( 25986216) Serum uric acid levels ( 30993211) Total cholesterol levels ( 30275531) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglycerides ( 30275531) Urate levels ( 31578528 23263486) Urate levels in lean individuals ( 25811787)
Interacting Genes		9 interacting genes: APOBEC1 CAVIN2 CELF2 FHL3 KHSRP REL SYNCRIP TNPO2 TRAF1	31 interacting genes: A1CF APOBEC1 APP CSDE1 EPRS1 ESR1 GRB2 HABP4 HMGA1 HMGA2 HNRNPD HNRNPK IL7R INSR IVNS1ABP KLHL3 NUPR1 PABPC1 PCSK7 PLCG1 PRMT1 PTPN11 SMN1 SYT1 SYT11 SYT2 SYT3 SYT4 SYT7 SYT8 SYT9
Entrez ID		29974	10492
HPRD ID		10627	06734
Ensembl ID		ENSG00000148584	ENSG00000135316
Uniprot IDs		A0A024QZI9 A0A024QZJ5 A0A024QZM7 B4E1E3 F8W9F8 Q9NQ94	B7Z645 O60506 Q59GL1
PDB IDs		2CPD	2DGU 2MXT 2NBB
Enriched GO Terms of Interacting Partners?
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