SYNCRIP and KLHL3

Number of citations of the paper that reports this interaction (PubMedID 10734137)
26

Data Source:
HPRD (in vitro)

		SYNCRIP	KLHL3
Description		synaptotagmin binding cytoplasmic RNA interacting protein	kelch like family member 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Endoplasmic Reticulum Membrane CRD-mediated MRNA Stability Complex Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex GAIT Complex Ribonucleoprotein Complex	Cytosol Cytoskeleton Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding Poly(A) Binding MRNA 5'-UTR Binding	Actin Binding Structural Molecule Activity Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Processing RNA Splicing Viral Process Negative Regulation Of Translation CRD-mediated MRNA Stabilization Cellular Response To Interferon-gamma	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Post-translational Protein Modification Ion Homeostasis Selective Autophagy Renal Sodium Ion Absorption Protein K48-linked Ubiquitination Distal Tubule Morphogenesis
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Bronchopulmonary dysplasia ( 23897914) Heart failure ( 31919418) Severe malaria ( 29381699) Severe malaria (adjusted for sickle cell variant rs334) ( 29381699)
Interacting Genes		31 interacting genes: A1CF APOBEC1 APP CSDE1 EPRS1 ESR1 GRB2 HABP4 HMGA1 HMGA2 HNRNPD HNRNPK IL7R INSR IVNS1ABP KLHL3 NUPR1 PABPC1 PCSK7 PLCG1 PRMT1 PTPN11 SMN1 SYT1 SYT11 SYT2 SYT3 SYT4 SYT7 SYT8 SYT9	16 interacting genes: AKT1 CFAP206 CUL3 GNAI1 GNAO1 KEAP1 KLHL12 MORF4L2 OPRD1 PPP3CA PRKACA SYNCRIP SYT2 WNK1 WNK3 WNK4
Entrez ID		10492	26249
HPRD ID		06734	09011
Ensembl ID		ENSG00000135316	ENSG00000146021
Uniprot IDs		B7Z645 O60506 Q59GL1	Q9UH77
PDB IDs		2DGU 2MXT 2NBB	4CH9 4HXI 5NKP
Enriched GO Terms of Interacting Partners?
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