UBE2T and PCGF2

Number of citations of the paper that reports this interaction (PubMedID 19690564)
57

Data Source:
BioGRID (two hybrid)

		UBE2T	PCGF2
Description		ubiquitin conjugating enzyme E2 T	polycomb group ring finger 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nuclear Chromatin Sex Chromatin Nucleus Nucleoplasm Nuclear Body PcG Protein Complex PRC1 Complex
	Molecular Function	Chromatin Binding Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Promoter-specific Chromatin Binding
	Biological Process	Protein Polyubiquitination DNA Repair Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Protein Ubiquitination Protein K29-linked Ubiquitination Interstrand Cross-link Repair Protein K27-linked Ubiquitination Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Chromatin Silencing Anterior/posterior Pattern Specification Histone Acetylation Histone H2A-K119 Monoubiquitination Embryonic Skeletal System Morphogenesis Cellular Response To Hydrogen Peroxide Negative Regulation Of G0 To G1 Transition Negative Regulation Of Apoptotic Signaling Pathway
Pathways		Fanconi Anemia Pathway Synthesis of active ubiquitin: roles of E1 and E2 enzymes	SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins Activation of anterior HOX genes in hindbrain development during early embryogenesis Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Breast cancer ( 23535733) Celiac disease ( 23936387)
Interacting Genes		22 interacting genes: AMFR ARIH2 BRCA1 CDK2 CHEK1 FANCD2 FANCL LNX2 MARCHF5 MGRN1 PCGF2 PRKCG PRKN RNF128 RNF144B RNF31 RNF4 ROCK1 RPS6KA1 TRIM27 UBA1 UBA6	21 interacting genes: ABHD6 CBX2 CBX6 CCND2 CD247 CTNNAL1 GJB5 HOXC9 HSF2 LMNA PHC2 RBCK1 RNF2 SPDEF UBE2D3 UBE2E2 UBE2Q2 UBE2T UBE2U USP11 USP7
Entrez ID		29089	7703
HPRD ID		13704	10621
Ensembl ID		ENSG00000077152	ENSG00000277258
Uniprot IDs		A0A024R9A9 Q9NPD8	A0A024R1V6 P35227
PDB IDs		1YH2 4CCG 5NGZ 5OJJ 6R75
Enriched GO Terms of Interacting Partners?
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