MED4 and CTNNBL1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MED4	CTNNBL1
Description		mediator complex subunit 4	catenin beta like 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Membrane Mediator Complex Core Mediator Complex	Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Centrosome Cytosol Membrane
	Molecular Function	Transcription Coregulator Activity Protein Binding Nuclear Receptor Transcription Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding	Protein Binding Enzyme Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated	MRNA Splicing, Via Spliceosome Apoptotic Process Somatic Diversification Of Immunoglobulins Positive Regulation Of Apoptotic Process
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Thiopurine-induced acute severe leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced early leukopenia in Crohn's disease ( 25108385) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe leukopenia in inflammatory bowel disease ( 29923122)	Bone mineral density ( 17903296) California verbal learning test score ( 31596458)
Interacting Genes		33 interacting genes: AMOT AP2M1 ATF7IP C1orf216 CCDC146 CCHCR1 CTDP1 CTNNBL1 FAM13C FOXJ3 FRMD6 FTCD HAUS1 KIFC3 LRRFIP1 MAB21L3 MCRS1 MED30 MED9 NDE1 PCBD2 PUM2 SDCBP SDCBP2 SGF29 SMARCD1 SMARCE1 SSX3 TLE5 TNFAIP8 TXLNA USHBP1 WDTC1	26 interacting genes: BEX3 BUD31 CALCOCO1 CATIP CDC5L CDCA7L CREBZF CWC15 HMGB1 HNRNPK IK LDOC1 LUC7L MAPK8IP2 MED4 MEOX2 NSRP1 PPP1R8 PRDM4 PRPF3 SPP1 SRPK2 STAMBP U2SURP WBP11 ZCCHC10
Entrez ID		29079	56259
HPRD ID		16145	10850
Ensembl ID		ENSG00000136146	ENSG00000132792
Uniprot IDs		A0A024RDY7 Q9NPJ6	Q8WYA6
PDB IDs			4CB8 4CB9 4CBA 4HM9 4HNM 4MFU 4MFV
Enriched GO Terms of Interacting Partners?
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