GRID2 and AP4M1

Number of citations of the paper that reports this interaction (PubMedID 14572453)
22

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		GRID2	AP4M1
Description		glutamate ionotropic receptor delta type subunit 2	adaptor related protein complex 4 subunit mu 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Ionotropic Glutamate Receptor Complex Cell Junction Dendritic Spine Synapse Postsynaptic Membrane Parallel Fiber To Purkinje Cell Synapse Postsynaptic Density Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane	Early Endosome Trans-Golgi Network Cytosol AP-4 Adaptor Complex Clathrin Adaptor Complex Endosome Lumen Trans-Golgi Network Membrane Extracellular Exosome
	Molecular Function	Ionotropic Glutamate Receptor Activity Protein Binding Glutamate Receptor Activity Ligand-gated Ion Channel Activity PDZ Domain Binding Signaling Receptor Activity Scaffold Protein Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	Protein Binding Protein Domain Specific Binding
	Biological Process	Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Glutamate Receptor Signaling Pathway Regulation Of Neuron Projection Development Cerebellar Granule Cell Differentiation Ion Transmembrane Transport Cellular Protein Localization Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Neuron Apoptotic Process Modulation Of Chemical Synaptic Transmission Positive Regulation Of Synapse Assembly Excitatory Postsynaptic Potential Prepulse Inhibition Regulation Of Postsynaptic Density Assembly Positive Regulation Of Long-term Synaptic Depression Excitatory Synapse Assembly	Protein Targeting Protein Targeting To Lysosome Intracellular Protein Transport Golgi To Endosome Transport Protein Localization Golgi To Lysosome Transport Protein Localization To Basolateral Plasma Membrane
Pathways			Lysosome Vesicle Biogenesis
Drugs		Glutamic Acid
Diseases			Cerebral palsy
GWAS		Coffee consumption ( 31046077) Intelligence (MTAG) ( 29326435) Manganese levels ( 26025379) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Obsessive-compulsive disorder ( 30456828) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		10 interacting genes: AP4M1 DLG2 EML1 GOPC GRIA1 GRID2IP GRIK2 GRIK5 MAGI2 PTPN4	14 interacting genes: AP4B1 ARF1 CACNG3 CD63 CHTF8 DDX52 GRID2 GRIN2A GRIN2B LAMP2 PMPCB TGOLN2 USP47 ZBTB22
Entrez ID		2895	9179
HPRD ID		06781	03803
Ensembl ID		ENSG00000152208	ENSG00000221838
Uniprot IDs		O43424	C9JC87 O00189
PDB IDs		5KC8 5KCA	3L81 4MDR
Enriched GO Terms of Interacting Partners?
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