GLRX and NFIC

Number of citations of the paper that reports this interaction (PubMedID 9417094)
21

Data Source:
HPRD (in vitro, in vivo)

		GLRX	NFIC
Description		glutaredoxin	nuclear factor I C
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Cytosol Extracellular Exosome	Nuclear Chromatin Fibrillar Center Nucleus Nucleoplasm
	Molecular Function	Electron Transfer Activity Glutathione Disulfide Oxidoreductase Activity Protein N-terminus Binding Glutathione Oxidoreductase Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity
	Biological Process	Nucleobase-containing Small Molecule Interconversion Electron Transport Chain Cell Redox Homeostasis Positive Regulation Of Membrane Potential Protein Deglutathionylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Transcription By RNA Polymerase II Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Interconversion of nucleotide di- and triphosphates	RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation
Drugs		Glutathione
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Metabolite levels ( 23823483) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)	Alzheimer's disease (APOE e4 interaction) ( 28183528) Automobile speeding propensity ( 30643258) HDL cholesterol ( 30275531) Heel bone mineral density ( 30598549) Height ( 28552196 20881960 25282103 31562340) Hip circumference ( 28552196) Hip circumference adjusted for BMI ( 28552196) Nevus count or cutaneous melanoma ( 30429480) Serum urate levels in chronic kidney disease ( 30181573) Weight ( 28552196)
Interacting Genes		7 interacting genes: AQP5 CASP3 GOT2 MAP3K5 MMP23B NFIC PTPN1	25 interacting genes: CBLC CREBBP DACH1 EPHA2 ERGIC1 FBXO7 GLIS1 GLIS2 GLRX LATS2 LLPH MAP2K3 MAPK14 MYC NFIB NSD3 RELA RFX1 SOX3 TEAD2 TKTL2 TLX1 TPD52L3 ZCCHC14 ZKSCAN7
Entrez ID		2745	4782
HPRD ID		02707	09009
Ensembl ID		ENSG00000173221	ENSG00000141905
Uniprot IDs		A0A024RAM2 P35754	B7Z4T6 P08651
PDB IDs		1B4Q 1JHB 4RQR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?