DESI1 and ZBTB46

Number of citations of the paper that reports this interaction (PubMedID 22370726)
44

Data Source:
BioGRID (affinity chromatography technology, enzymatic study)

		DESI1	ZBTB46
Description		desumoylating isopeptidase 1	zinc finger and BTB domain containing 46
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nuclear Chromatin
	Molecular Function	Peptidase Activity Identical Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Nucleic Acid Binding Metal Ion Binding
	Biological Process	Proteolysis	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Granulocyte Differentiation Negative Regulation Of Macrophage Differentiation Negative Regulation Of Monocyte Differentiation Negative Regulation Of Dendritic Cell Differentiation Positive Regulation Of Dendritic Cell Differentiation
Pathways
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) Neuroticism ( 29255261)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Birth weight ( 31043758) Coronary artery disease ( 29212778) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Marginal zone lymphoma or multiple sclerosis ( 31407831) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Multiple sclerosis ( 21833088) Obesity-related traits ( 23251661) Prostate cancer ( 23535732) Type 2 diabetes (adjusted for BMI) ( 30297969) Ulcerative colitis ( 28067908 21297633) Urinary albumin-to-creatinine ratio ( 31630189)
Interacting Genes		5 interacting genes: FGF7 RBX1 UBC XPO1 ZBTB46	1 interacting genes: DESI1
Entrez ID		27351	140685
HPRD ID		18590	16567
Ensembl ID		ENSG00000100418	ENSG00000130584
Uniprot IDs		Q6ICB0	A0A494BZW5 Q6ZMU8 Q86UZ6
PDB IDs		3EBQ
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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