RABGEF1 and DGCR6

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		RABGEF1	DGCR6
Description		RAB guanine nucleotide exchange factor 1	DiGeorge syndrome critical region gene 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Early Endosome Cytosol Early Endosome Membrane Recycling Endosome	Nucleus Extracellular Matrix
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Rab Guanyl-nucleotide Exchange Factor Activity Rab GTPase Binding	Molecular_function
	Biological Process	Protein Targeting To Membrane Endocytosis	Cell Adhesion Animal Organ Morphogenesis
Pathways		TBC/RABGAPs RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Aortic root size ( 21223598) Central corneal thickness ( 29760442)	Metabolite levels ( 23823483) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259)
Interacting Genes		29 interacting genes: AP1G1 BLOC1S6 CIPC DAZAP2 DGCR6 DNAJC5 GGA1 GGA2 HRAS KXD1 MON1A MON1B RAB33B RAB4A RABEP1 RNF11 RNF168 RPS27A TEAD4 THOC1 TRIM15 TRIM54 TXN2 UBB UBC UBE2D1 UBE2D3 YWHAB ZC2HC1C	61 interacting genes: ADAMTSL4 AGTRAP APP ARNT2 C1orf94 C3orf62 CBLL1 CBY2 CCDC33 CEP126 CTBP1 DEUP1 DLGAP2 DLX2 DNPEP DOCK8 EFEMP2 EFHC2 ENKD1 FBF1 GOLGA2 GSE1 HGS HOMEZ IHO1 IKZF3 KLHL12 LZTS2 MBIP MEIS2 MEOX2 MIA2 MID2 MIPOL1 NAB2 NECAB2 NOTCH2NLA NQO2 NUP54 NUP62 PDLIM7 PRDM14 RABGEF1 REL RFX6 RIMBP3 SPRY2 SS18L1 TCF12 TCF4 TFIP11 TLE5 TRAF1 TRAF2 TRIM27 TUBGCP4 VCP ZBED1 ZC4H2 ZNF398 ZNF446
Entrez ID		27342	8214
HPRD ID		11477	03177
Ensembl ID		ENSG00000154710	ENSG00000183628
Uniprot IDs		A0A024RDL6 A0A0A0MSJ3 A8K3R3 B3KMF1 Q9UJ41	Q14129 X5D7D2
PDB IDs		1TXU 2C7M 2C7N 2OT3 4N3X 4N3Y 4N3Z 4Q9U
Enriched GO Terms of Interacting Partners?
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