NDOR1 and EFHC2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		NDOR1	EFHC2
Description		NADPH dependent diflavin oxidoreductase 1	EF-hand domain containing 2
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cytoskeleton Perinuclear Region Of Cytoplasm	Microtubule
	Molecular Function	NADPH-hemoprotein Reductase Activity Protein Binding FMN Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Flavin Adenine Dinucleotide Binding NADP Binding	Calcium Ion Binding Protein Binding
	Biological Process	Cell Death Iron-sulfur Cluster Assembly Cellular Response To Menadione Oxidation-reduction Process	Regulation Of Neuron Projection Development Cellular Response To Leukemia Inhibitory Factor
Pathways		Cytosolic iron-sulfur cluster assembly
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular hemoglobin concentration ( 27863252) Mean corpuscular volume ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)	Mean arterial pressure ( 29403010)
Interacting Genes		8 interacting genes: CCDC33 CYCS DLG4 EFHC2 MTUS2 PMPCA TCF4 TCHP	37 interacting genes: ARHGEF5 ARMC7 CACNB4 CCDC120 CCHCR1 CCNG2 CDKN2A CLIC3 COPE CYFIP1 DGCR6 EDC3 EFHC1 EGLN3 EMD EXOC8 FAM107A HNRNPLL JAKMIP2 KIF9 LONRF1 MAPK9 NCDN NCK2 NDOR1 NR3C1 PBLD PLOD3 PTK6 RAD51D RUNX1T1 SNRNP25 SPG21 STK16 TRIM42 TSSK3 TUBGCP4
Entrez ID		27158	80258
HPRD ID		10444	06540
Ensembl ID		ENSG00000188566	ENSG00000183690
Uniprot IDs		Q9UHB4	Q5JST6
PDB IDs		4H2D	2Z13 2Z14
Enriched GO Terms of Interacting Partners?
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