BEX3 and SIVA1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		BEX3	SIVA1
Description		brain expressed X-linked 3	SIVA1 apoptosis inducing factor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Nucleoplasm Cytoplasm
	Molecular Function	Nerve Growth Factor Receptor Binding Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Identical Protein Binding Metal Ion Binding	Virus Receptor Activity Tumor Necrosis Factor Receptor Binding CD27 Receptor Binding Protein Binding Metal Ion Binding
	Biological Process	Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Multicellular Organism Development Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process	Viral Entry Into Host Cell Extrinsic Apoptotic Signaling Pathway
Pathways		NADE modulates death signalling
Drugs			Zinc
Diseases
GWAS			Endometrial cancer ( 27135401) Endometrial endometrioid carcinoma ( 27135401)
Interacting Genes		29 interacting genes: AIMP2 AKAP8L CACYBP CCDC116 CCDC85B CTNNBL1 DIABLO EMILIN1 FSD2 GOLGA8EP GOLGA8F MIF MNAT1 NECAB2 NGFR NTRK3 PTPN13 SIVA1 SMPD1 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 TSC1 USHBP1 VTA1 YWHAE	20 interacting genes: ABL2 APP BAG5 BCL2L1 BEX3 CD27 CD4 CDKN2A MEFV NEDD4 NEDD4L PCNA POLR2M PXMP2 RAD18 RHOU SSBP3 TCAP TNFRSF4 UBE2D1
Entrez ID		27018	10572
HPRD ID		02291	16124
Ensembl ID		ENSG00000166681	ENSG00000184990
Uniprot IDs		Q00994	O15304
PDB IDs		1SA6
Enriched GO Terms of Interacting Partners?
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